{"id":"W2275966295","doi":"10.1182/blood.v124.21.314.314","title":"Selective Photodepletion of Recipient-Alloreactive T-Cells Enables Safe and Efficacious Haploidentical HSCT: Initial Results from a Phase 2 Trial in Patients with AML, ALL, and MDS","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Hospital; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Medicine; Hematopoietic stem cell transplantation; Graft-versus-host disease; Immunology; Leukemia; Internal medicine; CD34; Clinical trial; Phases of clinical research; Stem cell; Transplantation; Oncology; Gastroenterology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001812493,0.001032099,0.001318131,0.0003939416,0.0003305883,0.0007573427,0.0005176658,0.000750414,0.001688718],"category_scores_gemma":[0.0004887086,0.0003443599,0.0007664692,0.0002900005,0.0007210005,0.0005344365,0.0003361212,0.001714014,0.0002839362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004315223,"about_ca_system_score_gemma":0.0006278819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004206498,"about_ca_topic_score_gemma":0.000801359,"domain_scores_codex":[0.9995165,0.0002465207,0.00003041638,0.00007731696,0.00003579806,0.00009352677],"domain_scores_gemma":[0.9996722,0.00007456214,0.00005652237,0.00004637862,0.00002005832,0.0001303835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3731017,0.1580195,0.01025656,0.001245755,0.001248645,0.0005331381,0.0008536696,0.00531921,0.2435909,0.000679963,0.002610315,0.2025407],"study_design_scores_gemma":[0.2156175,0.7385074,0.01029698,0.00004111239,0.0005091416,0.0004523163,0.00007623716,0.001231,0.03048794,0.0001827501,0.002564314,0.00003321695],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968836,0.001037287,0.000513687,0.0001008066,0.00002656722,0.0007194934,0.0002002623,0.00003248677,0.000485733],"genre_scores_gemma":[0.9962831,0.0006916517,0.001057065,0.0001501668,0.00006307354,0.0007127056,0.000427021,0.00001255885,0.0006025968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001812493,"threshold_uncertainty_score":0.00958544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01100352527089692,"score_gpt":0.257274373052014,"score_spread":0.2462708477811171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}