{"id":"W2276189378","doi":"10.1016/j.jaci.2015.10.047","title":"Innate mechanisms can predict successful allergy immunotherapy","year":2016,"lang":"en","type":"letter","venue":"Journal of Allergy and Clinical Immunology","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children; SickKids Foundation","funders":"Universität Zürich; European Commission; Allergopharma; GlaxoSmithKline; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Immunotherapy; Allergy; Immunology; Immunoglobulin E; Allergen immunotherapy; Medicine; Allergen; Immune system; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001661113,0.0005450914,0.0009624308,0.0004628675,0.0007545326,0.001468901,0.0004992309,0.008330994,0.003724539],"category_scores_gemma":[0.01410608,0.0003078487,0.0007178488,0.0002174911,0.001193002,0.001792024,0.0005602201,0.01131632,0.002512284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000808362,"about_ca_system_score_gemma":0.0006313472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000576484,"about_ca_topic_score_gemma":0.001147277,"domain_scores_codex":[0.9988326,0.0004069339,0.0002168165,0.000119877,0.0002549657,0.0001688311],"domain_scores_gemma":[0.9949104,0.003620042,0.0003054816,0.0002469503,0.0005008081,0.0004161875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.001152806,0.0006568261,0.151728,0.0004319127,0.0002082544,0.08749648,0.000575872,0.0009304263,0.003807135,0.01179494,0.5457036,0.1955138],"study_design_scores_gemma":[0.001081833,0.001709789,0.1221576,0.002046072,0.0004518133,0.2420528,0.001668221,0.01302455,0.003450657,0.09613346,0.5159553,0.0002679561],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.03589456,0.01432295,0.001144287,0.8934779,0.02736745,0.00004788452,0.0001587778,0.00008904307,0.02749714],"genre_scores_gemma":[0.4371258,0.01205611,0.002504563,0.3474465,0.1829694,0.000117841,0.0002768987,0.00005124519,0.01745178],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.008330994,"threshold_uncertainty_score":0.01245987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01979655321912047,"score_gpt":0.2930241099027782,"score_spread":0.2732275566836577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}