{"id":"W2276340295","doi":"10.3310/hta20100","title":"OPTIMA prelim: a randomised feasibility study of personalised care in the treatment of women with early breast cancer","year":2016,"lang":"en","type":"article","venue":"Health Technology Assessment","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Ontario Institute for Cancer Research","funders":"Health Technology Assessment Programme; Medical Research Council; National Institute for Health and Care Research","keywords":"Medicine; Breast cancer; Oncology; Internal medicine; Randomized controlled trial; Chemotherapy; Cancer; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01277809,0.002218202,0.00309951,0.0009959888,0.00099757,0.001866624,0.001597398,0.004578102,0.02288265],"category_scores_gemma":[0.02666174,0.001254843,0.003345183,0.0006853402,0.002912389,0.002392705,0.002549801,0.003556279,0.002014331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002332204,"about_ca_system_score_gemma":0.004992642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002022218,"about_ca_topic_score_gemma":0.001725188,"domain_scores_codex":[0.9834432,0.0134055,0.0008071923,0.001060491,0.0005689813,0.0007147379],"domain_scores_gemma":[0.984664,0.008718274,0.002826901,0.001097453,0.0006750501,0.002018334],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9622127,0.01498566,0.0005428271,0.002526023,0.000554809,0.00008140323,0.0003117605,0.0007842412,0.0006080741,0.0005292987,0.0008717918,0.0159913],"study_design_scores_gemma":[0.8938457,0.1024926,0.0008862567,0.0002509318,0.0002387185,0.00002645642,0.00009518403,0.000347805,0.00009292121,0.0005488661,0.001151693,0.00002298742],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7367888,0.005146396,0.005883364,0.004779694,0.0029258,0.2334133,0.002571168,0.000327542,0.008163936],"genre_scores_gemma":[0.7182841,0.001691693,0.01467234,0.00319115,0.0009410516,0.2554774,0.0007060166,0.00003968262,0.004996594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02288265,"threshold_uncertainty_score":0.07655007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01459447802586401,"score_gpt":0.3372890086815146,"score_spread":0.3226945306556506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}