{"id":"W2276407897","doi":"10.1074/jbc.m115.679969","title":"The Solution Structure of the Lantibiotic Immunity Protein NisI and Its Interactions with Nisin","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Herbal Medicine Research Studies","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Marine Biosciences","funders":"Deutsche Forschungsgemeinschaft","keywords":"Lantibiotics; Nisin; Immunity; Microbiology; Chemistry; Bacteriocin; Biology; Computational biology; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003291468,0.00006778449,0.0001887637,0.00000863289,0.0000879568,0.000006696015,0.0001120545,0.00005552796,0.00001213335],"category_scores_gemma":[0.002271064,0.00002247496,0.00004124321,0.0000928793,0.0002809594,0.00002420259,0.00007993935,0.0005564435,2.537264e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004846311,"about_ca_system_score_gemma":0.0001259879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006133096,"about_ca_topic_score_gemma":0.000002353125,"domain_scores_codex":[0.9993131,0.00006950408,0.0002030995,0.0000533161,0.0002469008,0.0001140693],"domain_scores_gemma":[0.9991122,0.000132163,0.0001902107,0.0001044724,0.0003561698,0.0001047584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000424157,0.00005212686,0.0093432,0.00006844911,0.0000920894,0.00001198624,0.00007744638,0.000001029952,0.9889296,0.000005682689,0.0003880396,0.0006062091],"study_design_scores_gemma":[0.001437357,0.001062453,0.06604022,0.00075294,0.00007050612,0.001072962,0.001799388,0.00004280229,0.9254286,0.0002189252,0.002007006,0.000066799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932629,0.001453771,0.000008757312,0.004731935,0.00003083187,0.0001202352,0.000003314721,0.000002986107,0.0003852554],"genre_scores_gemma":[0.99946,0.00008653424,0.00007767764,0.00002602227,0.0001475459,4.504749e-7,6.17731e-7,0.000002416348,0.0001987233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06350093,"threshold_uncertainty_score":0.271884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0545739371285406,"score_gpt":0.332570404632816,"score_spread":0.2779964675042754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}