{"id":"W2276682288","doi":"10.1152/ajpregu.2000.279.5.r1707","title":"Ca2+binding to cardiac troponin C: effects of temperature and pH on mammalian and salmonid isoforms","year":2000,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Chemistry; Troponin C; Rainbow trout; Calcium; Contractility; Biophysics; Troponin; Gene isoform; Trout; Biochemistry; Internal medicine; Endocrinology; Biology; Fish ","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003446381,0.0002595316,0.0002706409,0.00009766929,0.0001588054,0.0003072676,0.0003571819,0.000417009,0.001680726],"category_scores_gemma":[0.0004746104,0.0002849596,0.0003067243,0.00014741,0.0004635599,0.0003148333,0.0002572383,0.0004052294,0.0003265696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000597199,"about_ca_system_score_gemma":0.0002509005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003976689,"about_ca_topic_score_gemma":0.004863423,"domain_scores_codex":[0.9997507,0.00003393729,0.00002797573,0.00005977103,0.00006571649,0.00006188907],"domain_scores_gemma":[0.9996997,0.00006392136,0.00007958427,0.00002793133,0.00004814443,0.00008067082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005055713,0.00001435434,0.000893824,0.00003334516,0.000007810918,0.00002427537,0.0000216184,0.00007654112,0.9978897,0.00001991949,0.00003348196,0.000479583],"study_design_scores_gemma":[0.00004931893,0.0007139513,0.1264043,0.00001222878,0.00002873781,0.0004583347,0.00009735514,0.002529833,0.8684998,0.00005545383,0.001130578,0.00002004715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979231,0.0007269237,0.0003870886,0.00005855324,0.00001015939,0.00001114752,0.0001866091,0.00001097832,0.0006854769],"genre_scores_gemma":[0.9969987,0.0003413126,0.0008658154,0.00008992445,0.000007469598,0.0000185023,0.0005674293,0.00001793684,0.001092933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003976689,"threshold_uncertainty_score":0.007907093,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00820946517033933,"score_gpt":0.2382019258612252,"score_spread":0.2299924606908859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}