{"id":"W2277485511","doi":"10.1016/j.bbcan.2016.02.004","title":"Melatonin and the von Hippel–Lindau/HIF-1 oxygen sensing mechanism: A review","year":2016,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Reviews on Cancer","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Melatonin; Angiogenesis; Ubiquitin ligase; Hypoxia-inducible factors; Cell biology; Biology; Chemistry; Ubiquitin; Cancer research; Endocrinology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003850524,0.0007964164,0.001247765,0.00175315,0.0002940864,0.0009441174,0.0008629748,0.0009647401,0.002611998],"category_scores_gemma":[0.0004325271,0.0002741139,0.0004298786,0.001781956,0.0004254435,0.001128954,0.000669577,0.001358179,0.001252655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000571182,"about_ca_system_score_gemma":0.001183687,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001460047,"about_ca_topic_score_gemma":0.002931569,"domain_scores_codex":[0.999898,0.00001457861,0.00001739913,0.00002390654,0.00003352037,0.00001267372],"domain_scores_gemma":[0.9998603,0.00004819999,0.000031238,0.000004782687,0.00003506135,0.00002038185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002342505,0.0001134545,0.0003996133,0.02415692,0.0001870954,0.0004381241,0.00009613806,0.0002968193,0.005018339,0.003119173,0.04347115,0.9224688],"study_design_scores_gemma":[0.0000329812,0.000115084,0.001134468,0.001917794,0.000211583,0.001057867,0.00006172367,0.00006002248,0.0007607108,0.001398927,0.993223,0.0000258806],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008494129,0.999331,0.00004542142,0.0001399394,0.0001126178,0.000002100491,0.00001297082,0.000003690368,0.0002672685],"genre_scores_gemma":[0.0006375143,0.9985756,0.0001053182,0.000139188,0.0002095989,0.000004239145,0.00002593074,8.410724e-7,0.0003017637],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002611998,"threshold_uncertainty_score":0.008737981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02991439591038548,"score_gpt":0.3289910452498629,"score_spread":0.2990766493394774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}