{"id":"W2277731646","doi":"10.1056/nejmoa1509024","title":"Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis","year":2016,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":315,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"Wellcome Trust","keywords":"Medicine; Cryptococcal meningitis; Dexamethasone; Meningitis; Human immunodeficiency virus (HIV); Immunology; Cryptococcus neoformans; Cryptococcosis; Adjuvant; Virology; Viral disease; Internal medicine; Pediatrics; Microbiology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009540675,0.0006037661,0.001622255,0.0003873897,0.0002522197,0.0004879774,0.0005913971,0.0008814281,0.002682335],"category_scores_gemma":[0.001702214,0.0001845847,0.0006809975,0.0004579105,0.0004334899,0.0003111956,0.0003258966,0.001733323,0.0002113142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003745931,"about_ca_system_score_gemma":0.00064247,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006306199,"about_ca_topic_score_gemma":0.001096283,"domain_scores_codex":[0.9995661,0.0002409672,0.0000552058,0.00004151247,0.00005095478,0.0000452228],"domain_scores_gemma":[0.999112,0.0003979678,0.0002029851,0.00003167239,0.00004630465,0.0002090603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6138896,0.01245132,0.007902401,0.01126057,0.001409686,0.0006904993,0.0002510702,0.0008557287,0.007574745,0.000397959,0.001539654,0.3417767],"study_design_scores_gemma":[0.6492218,0.3131579,0.01964058,0.001936168,0.001651385,0.001062869,0.0001848339,0.0007747564,0.003421889,0.0005148867,0.008399675,0.00003337085],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9079156,0.08663037,0.0003773001,0.0006974965,0.0007884048,0.001245549,0.0002130583,0.00004380747,0.002088459],"genre_scores_gemma":[0.9769973,0.02043881,0.0005401128,0.0004114465,0.0005841641,0.0004278982,0.000136325,0.000002653637,0.0004612709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002682335,"threshold_uncertainty_score":0.0089733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0232962640798178,"score_gpt":0.2836871160936005,"score_spread":0.2603908520137828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}