{"id":"W2277878259","doi":"10.1128/jvi.00017-16","title":"VP8, the Major Tegument Protein of Bovine Herpesvirus 1, Interacts with Cellular STAT1 and Inhibits Interferon Beta Signaling","year":2016,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Light Source (Canada); University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Biology; STAT1; STAT2; STAT protein; Phosphorylation; Immunoprecipitation; Interferon; Transfection; Molecular biology; Signal transduction; Cytoplasm; Tyrosine; Cell biology; Virology; Biochemistry; STAT3; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007612882,0.0003458927,0.0001849906,0.00009725144,0.0001663489,0.0002253392,0.0001925865,0.000236435,0.00118178],"category_scores_gemma":[0.00009434784,0.00008770332,0.0002300832,0.00009071585,0.0002042557,0.0001505518,0.0001661443,0.0003104749,0.0003688963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003419474,"about_ca_system_score_gemma":0.0001106534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002174229,"about_ca_topic_score_gemma":0.0002438042,"domain_scores_codex":[0.9998918,0.00002111914,0.000007234575,0.00001831944,0.00002836754,0.00003317549],"domain_scores_gemma":[0.9999487,0.00001474144,0.00001581341,0.000005199524,0.000005094601,0.00001035347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001830564,0.00002043035,0.0003378141,0.00005583582,0.00000668147,0.00002685708,0.000007036925,0.00005601085,0.998117,0.00004118331,0.00003727937,0.001110943],"study_design_scores_gemma":[0.00002991899,0.0003544705,0.009767398,0.00001111411,0.00002293721,0.0003727335,0.0000261157,0.001024518,0.9846297,0.00004122585,0.003715955,0.000003908885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939943,0.00421549,0.0009155404,0.00006720288,0.00002372585,0.000006569533,0.0001436378,0.00003000238,0.0006034896],"genre_scores_gemma":[0.9961563,0.00119089,0.0009528864,0.00004084012,0.00001547441,0.0000182737,0.0005731072,0.0000102261,0.001042138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00118178,"threshold_uncertainty_score":0.003953457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01006402290020942,"score_gpt":0.2445775394062284,"score_spread":0.234513516506019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}