{"id":"W2277896810","doi":"10.1021/acs.biochem.5b00274","title":"YehZYXW of <i>Escherichia coli</i> Is a Low-Affinity, Non-Osmoregulatory Betaine-Specific ABC Transporter","year":2015,"lang":"en","type":"article","venue":"Biochemistry","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Betaine; Osmolyte; Biochemistry; Periplasmic space; ATP-binding cassette transporter; Chemistry; Escherichia coli; Osmotic concentration; Proline; Biology; Transporter; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001694155,0.0002911543,0.0003091696,0.00003682992,0.0000428743,0.00001800577,0.0004551889,0.00069119,0.00005682094],"category_scores_gemma":[0.00001803012,0.0002933428,0.0001787695,0.0001630257,0.0003456942,0.000002998817,0.000145094,0.0001599269,0.00001523775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002067723,"about_ca_system_score_gemma":0.0002258549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001041269,"about_ca_topic_score_gemma":0.000002542391,"domain_scores_codex":[0.9984672,0.00001765465,0.0004077534,0.0005434142,0.0002078368,0.0003561628],"domain_scores_gemma":[0.9986342,0.000003978133,0.000173244,0.0007796119,0.0001994186,0.0002095955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001602978,0.0001512088,0.0007695933,0.00006854165,0.0000595116,0.00000519502,0.00004372268,0.000002227946,0.9820921,0.000007979233,0.01599175,0.0006479037],"study_design_scores_gemma":[0.0009282937,0.0002307988,0.001249442,0.00002565671,0.00002494233,0.00001020491,0.00006943777,0.000008636179,0.9517184,0.00004715161,0.04535871,0.0003283021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961465,0.001203231,0.0001403206,0.0002463853,0.0002426931,0.0001570816,0.0001369022,0.00002443008,0.001702457],"genre_scores_gemma":[0.997013,0.0002422788,0.001076727,0.0003675499,0.000434863,0.00001745667,0.000233226,0.00004230901,0.0005725977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03037365,"threshold_uncertainty_score":0.9999519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01149221607458117,"score_gpt":0.2155250685870254,"score_spread":0.2040328525124442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}