{"id":"W2277945632","doi":"10.1016/j.ctrv.2016.02.004","title":"Clinical predictors of benefit from fulvestrant in advanced breast cancer: A Meta-analysis of randomized controlled trials","year":2016,"lang":"en","type":"review","venue":"Cancer Treatment Reviews","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Manitoba; University of Toronto; CancerCare Manitoba","funders":"","keywords":"Medicine; Fulvestrant; Randomized controlled trial; Meta-analysis; Oncology; Breast cancer; Internal medicine; Clinical trial; Cancer; Tamoxifen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","metaepi_broad"],"consensus_categories":["metaepi_broad"],"category_scores_codex":[0.004519354,0.0009595955,0.05315254,0.0003189409,0.00002047496,0.000009155586,0.0003549285,0.0007578231,0.0004816568],"category_scores_gemma":[0.0005105703,0.000399928,0.03609319,0.0004753463,0.0002117695,0.000005277126,0.00005202432,0.0001707402,0.000004364872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001324784,"about_ca_system_score_gemma":0.0005854046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004572333,"about_ca_topic_score_gemma":0.0001776484,"domain_scores_codex":[0.9860431,0.005280824,0.007175719,0.0009477169,0.0002380252,0.0003145911],"domain_scores_gemma":[0.9902179,0.001810861,0.006695293,0.0009895968,0.0001242641,0.0001621071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.01087447,0.0002356342,0.00006566229,0.0009201024,0.4617884,0.00000275828,0.000008426689,0.00001276079,0.00005604641,0.000004452569,0.00003908172,0.5259922],"study_design_scores_gemma":[0.0740203,0.0001909071,0.000007423366,0.003488538,0.6871082,0.000001046642,0.000001013035,0.000002144413,0.00007465044,0.000003967897,0.2348175,0.000284323],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006767675,0.9853923,0.00001407219,0.00002929068,0.00033417,0.008847921,0.004631273,0.000005847758,0.0000682994],"genre_scores_gemma":[0.0001438739,0.9883971,0.00008716996,0.00001559555,0.000257983,0.009874299,0.000797943,0.0000492472,0.0003768136],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5257078,"threshold_uncertainty_score":0.9998453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09100272314250009,"score_gpt":0.429785304232966,"score_spread":0.3387825810904659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}