{"id":"W2278124160","doi":"10.1007/0-306-46862-x_59","title":"Structure-activity relationships in cyclic ß-sheet antibacterial peptides","year":2005,"lang":"en","type":"book-chapter","venue":"Kluwer Academic Publishers eBooks","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Bio-Systems (Canada); University of British Columbia; University of Alberta","funders":"","keywords":"Antibacterial peptide; Cyclic peptide; Antibacterial activity; Beta sheet; Chemistry; Materials science; Peptide; Biochemistry; Biology; Bacteria; Paleontology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0005263291,0.0009304874,0.001165195,0.0007339282,0.0003514485,0.0002258676,0.0008390517,0.004117925,0.002371355],"category_scores_gemma":[0.0001478582,0.0009383072,0.0003571768,0.00005057339,0.0008809266,0.001185551,0.0003704902,0.006944719,0.0003788423],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003637825,"about_ca_system_score_gemma":0.0003262601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001832033,"about_ca_topic_score_gemma":0.0003326096,"domain_scores_codex":[0.9966797,0.0002209307,0.000944335,0.001062079,0.0001421602,0.0009508017],"domain_scores_gemma":[0.9981581,0.0002969648,0.000718399,0.0006461837,0.00009075649,0.00008958395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001312925,0.000102817,0.002284686,0.0002391388,0.00129159,0.00007356291,0.002606691,0.00003916153,0.4883469,0.05505428,0.3907176,0.05793062],"study_design_scores_gemma":[0.002240195,0.000106547,0.003046707,0.0006040701,0.0002144039,0.0002079936,0.0001291211,0.000002485912,0.01288093,0.01314048,0.9655447,0.00188239],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.1623852,0.001100554,0.00001684263,0.0006143074,0.003203633,0.0009488142,0.0006484397,0.0003464029,0.8307358],"genre_scores_gemma":[0.5135161,0.00005349913,0.00005642249,0.000273777,0.000582275,0.00001137582,0.0004230813,0.000122617,0.4849608],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.574827,"threshold_uncertainty_score":0.9993067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02690477846102912,"score_gpt":0.2368995734515998,"score_spread":0.2099947949905707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}