{"id":"W2278381545","doi":"10.1021/acs.orglett.5b02060","title":"Structure and Biogenesis of Roussoellatide, a Dichlorinated Polyketide from the Marine-Derived Fungus <i>Roussoella</i> sp. DLM33","year":2015,"lang":"en","type":"article","venue":"Organic Letters","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Natural Sciences and Engineering Research Council of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Polyketide; Biogenesis; Chemistry; Carbon skeleton; Metabolite; Fungus; Stereochemistry; Intermolecular force; Molecule; Organic chemistry; Biosynthesis; Biochemistry; Botany; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001341515,0.000318258,0.0001775825,0.0002339256,0.000240502,0.0004532188,0.0002017913,0.0003033159,0.0003348585],"category_scores_gemma":[0.0001381368,0.0001478846,0.0001897487,0.0002071176,0.0002640374,0.0003456586,0.0002778012,0.0003332168,0.000291764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003487585,"about_ca_system_score_gemma":0.0003399797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00079459,"about_ca_topic_score_gemma":0.0008371786,"domain_scores_codex":[0.9999141,0.00001819994,0.000008418155,0.00002608312,0.00001449544,0.00001865979],"domain_scores_gemma":[0.9998838,0.000009936206,0.00004159613,0.00001779705,0.00001587963,0.00003101633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001242144,0.000008681134,0.0007132515,0.00004530675,0.000004007428,0.0004197282,0.0001028201,0.0002497248,0.9952446,0.0004575396,0.0000191015,0.002611068],"study_design_scores_gemma":[0.00001346845,0.0003056977,0.01475145,0.00001973448,0.00002121447,0.00115161,0.0001881082,0.0006102493,0.9752377,0.0003451444,0.007334056,0.00002164814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937331,0.001427391,0.002277418,0.00007630645,0.00001095999,0.00001970958,0.0004132112,0.0000251967,0.002016533],"genre_scores_gemma":[0.9936048,0.0007195771,0.003652403,0.00003075239,0.000005116919,0.000009137367,0.0006774654,0.00001122887,0.001289585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00079459,"threshold_uncertainty_score":0.002530456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01072224318757857,"score_gpt":0.1992818111514061,"score_spread":0.1885595679638275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}