{"id":"W2278381545","doi":"10.1021/acs.orglett.5b02060","title":"Structure and Biogenesis of Roussoellatide, a Dichlorinated Polyketide from the Marine-Derived Fungus <i>Roussoella</i> sp. DLM33","year":2015,"lang":"en","type":"article","venue":"Organic Letters","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Natural Sciences and Engineering Research Council of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Polyketide; Biogenesis; Chemistry; Carbon skeleton; Metabolite; Fungus; Stereochemistry; Intermolecular force; Molecule; Organic chemistry; Biosynthesis; Biochemistry; Botany; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001531685,0.0002412876,0.0003932726,0.00005472538,0.00006764041,0.00002889474,0.000179774,0.0001152802,0.0004128235],"category_scores_gemma":[0.0002549508,0.0001432345,0.00006970267,0.0003256549,0.0001716011,0.00005915665,0.0001757313,0.0002127585,0.00001594509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000615824,"about_ca_system_score_gemma":0.00006905109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001755339,"about_ca_topic_score_gemma":0.000156402,"domain_scores_codex":[0.9987214,0.000073688,0.0002993009,0.0003762238,0.0002618656,0.0002675302],"domain_scores_gemma":[0.9989938,0.0001165819,0.0001550494,0.0004770392,0.00009874557,0.0001588141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002285807,0.00002208985,0.02222619,0.00002453895,0.0001531208,0.00002692643,0.0003353476,4.700375e-7,0.9629613,0.000005018085,0.0113452,0.002671198],"study_design_scores_gemma":[0.001110247,0.00009020669,0.04727366,0.00004798282,0.0002623769,0.0000761796,0.0001177575,0.000007099866,0.9472083,0.00004102417,0.003570819,0.0001942805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9699538,0.0009352983,0.00000812001,0.02833802,0.0002510705,0.0003082579,0.000101101,0.00005292194,0.00005136315],"genre_scores_gemma":[0.992654,0.0001266448,0.0005362008,0.006073367,0.0004193403,3.493078e-7,0.00006233049,0.00004236932,0.00008535574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02504747,"threshold_uncertainty_score":0.5840933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01072224318757857,"score_gpt":0.1992818111514061,"score_spread":0.1885595679638275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}