{"id":"W2278622931","doi":"10.69645/wzqs6265","title":"RAS and RAF signaling in melanoma: biology and therapies","year":2010,"lang":"en","type":"article","venue":"˜The œbiomedical & life sciences collection.","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Melanoma; Cancer research; Biology; Computational biology; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007218637,0.0001011012,0.0001170511,0.00009516084,0.0003680037,0.0000366761,0.0001777964,0.0001566962,0.00004033451],"category_scores_gemma":[0.0001410493,0.00006492869,0.00002382132,0.0003444806,0.001283722,0.000005498041,0.0001078912,0.0001542932,0.000002415788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003475527,"about_ca_system_score_gemma":0.0001580037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001079366,"about_ca_topic_score_gemma":0.0004625312,"domain_scores_codex":[0.9990787,0.00008501529,0.0001656821,0.0003308721,0.0001147006,0.0002250553],"domain_scores_gemma":[0.9996108,0.00007894967,0.00004629314,0.0001170806,0.00002284368,0.0001240349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000362018,0.00004649226,0.02917426,0.000007032623,0.00001789431,0.000001995624,0.0002743715,0.000001117163,0.9637361,0.0009068516,0.002057124,0.003740633],"study_design_scores_gemma":[0.005989298,0.005103627,0.1193838,0.00005046621,0.00006435512,0.0006133375,0.003426414,0.003646367,0.07237508,0.01816931,0.769762,0.001415852],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955848,0.00131668,0.0004849645,0.00116999,0.0005049994,0.0001316005,0.000004345589,0.00001002488,0.0007925296],"genre_scores_gemma":[0.9981952,0.0001608982,0.0005478245,0.000464283,0.000298145,0.00002204581,0.000006555308,0.000004798636,0.0003002914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8913609,"threshold_uncertainty_score":0.4729926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01114550138047864,"score_gpt":0.2619218096529252,"score_spread":0.2507763082724465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}