{"id":"W2278622931","doi":"10.69645/wzqs6265","title":"RAS and RAF signaling in melanoma: biology and therapies","year":2010,"lang":"en","type":"article","venue":"The biomedical & life sciences collection.","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Melanoma; Cancer research; Biology; Computational biology; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009084468,0.0004444536,0.0004345816,0.00170596,0.0004149218,0.0007279647,0.0003163989,0.0004801569,0.003964689],"category_scores_gemma":[0.0003112944,0.0002206184,0.0002154751,0.0005890903,0.000503775,0.0004855442,0.0005220588,0.001589478,0.001641772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007167144,"about_ca_system_score_gemma":0.0009914705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001047017,"about_ca_topic_score_gemma":0.004189485,"domain_scores_codex":[0.9998195,0.00004109602,0.00001171216,0.00001516534,0.00008143323,0.00003123797],"domain_scores_gemma":[0.9998544,0.00002374875,0.00001159616,0.0000167618,0.00003991299,0.00005357237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002480034,0.0008519254,0.004255658,0.001207545,0.00007063498,0.001066856,0.000192352,0.0008962743,0.1576431,0.0201848,0.07314879,0.7380019],"study_design_scores_gemma":[0.0005899356,0.00154702,0.02606969,0.0005197258,0.0001136236,0.006055048,0.0002397647,0.001227142,0.1050254,0.0127833,0.8457651,0.00006434529],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1123856,0.7728215,0.003525248,0.04291157,0.00155472,0.0002102622,0.001402975,0.0002935329,0.06489458],"genre_scores_gemma":[0.2451599,0.6874205,0.004728772,0.001660585,0.002529575,0.0001735683,0.001366156,0.0000466606,0.05691427],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003964689,"threshold_uncertainty_score":0.01326323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01114550138047864,"score_gpt":0.2619218096529252,"score_spread":0.2507763082724465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}