{"id":"W2278623109","doi":"10.1021/acs.biochem.5b00921","title":"Characterization of Vis Toxin, a Novel ADP-Ribosyltransferase from <i>Vibrio splendidus</i>","year":2015,"lang":"en","type":"article","venue":"Biochemistry","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; York University; University of Toronto; Ontario Institute for Cancer Research; University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"NAD+ kinase; Enzyme; Biochemistry; Agmatine; Toxin; Biology; Molecular mass; Transferase; Molecular biology; Chemistry; Putrescine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007614727,0.0003221047,0.0002996252,0.0002273308,0.00009141883,0.0002921506,0.0001591146,0.0002500358,0.0004121175],"category_scores_gemma":[0.0001346245,0.00007911283,0.0003875971,0.0003480439,0.0001368606,0.0001647412,0.0001480011,0.0003197351,0.0003595011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002526305,"about_ca_system_score_gemma":0.0002452596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001359098,"about_ca_topic_score_gemma":0.0008735275,"domain_scores_codex":[0.9999453,0.000004649119,0.000005010384,0.00001220421,0.00002384337,0.000009063519],"domain_scores_gemma":[0.9999179,0.000008667834,0.00002738466,0.000006115764,0.00001964899,0.00002025714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004199626,0.00001422755,0.0007693256,0.00003502633,0.000005021501,0.0001023026,0.00001150879,0.0001572217,0.9974689,0.00003947818,0.00004428419,0.001310762],"study_design_scores_gemma":[0.00002908996,0.0007186109,0.03330098,0.0000151014,0.00005178541,0.002214261,0.0001072334,0.002856173,0.946821,0.00009455701,0.01377497,0.00001616696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893445,0.001521414,0.005737969,0.0001553737,0.00002156211,0.00004771043,0.001915775,0.00008372868,0.001171886],"genre_scores_gemma":[0.9732896,0.001582707,0.01059568,0.0001371781,0.00001670545,0.00002497408,0.01121205,0.00004168048,0.003099338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001359098,"threshold_uncertainty_score":0.002702415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01431969716842946,"score_gpt":0.2121548369460061,"score_spread":0.1978351397775766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}