{"id":"W2278623109","doi":"10.1021/acs.biochem.5b00921","title":"Characterization of Vis Toxin, a Novel ADP-Ribosyltransferase from <i>Vibrio splendidus</i>","year":2015,"lang":"en","type":"article","venue":"Biochemistry","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; York University; University of Toronto; Ontario Institute for Cancer Research; University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"NAD+ kinase; Enzyme; Biochemistry; Agmatine; Toxin; Biology; Molecular mass; Transferase; Molecular biology; Chemistry; Putrescine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001102892,0.0001949224,0.0002746494,0.00003378655,0.00004939086,0.00001230486,0.0002525112,0.0003495733,0.000624796],"category_scores_gemma":[0.00005818481,0.0001927679,0.00009653121,0.0001049181,0.0001026163,0.00007921517,0.00006197441,0.0001757446,0.0001463932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003804023,"about_ca_system_score_gemma":0.0001381842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001443621,"about_ca_topic_score_gemma":0.000003177502,"domain_scores_codex":[0.9990322,0.00002797861,0.0003259288,0.0003068458,0.00005773008,0.0002493471],"domain_scores_gemma":[0.9993035,0.00002150335,0.0001285734,0.0003984644,0.00009842995,0.00004958372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001417431,0.0002041202,0.0001591696,0.00001789268,0.00008163246,0.000001520605,0.0002143364,1.924541e-7,0.9978132,0.00007092933,0.000697923,0.0005973722],"study_design_scores_gemma":[0.001628354,0.00008214266,0.000513578,0.00004886952,0.000037257,0.00001515911,0.0001412734,0.000003434871,0.9801828,0.00002870704,0.01711307,0.0002053823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936529,0.0006617544,0.002834464,0.0001016536,0.0006622109,0.0001266591,0.001331777,0.00006763067,0.0005609714],"genre_scores_gemma":[0.9955087,0.00004480174,0.0003516678,0.0001612093,0.00008170588,0.00001539903,0.002177338,0.00002326251,0.001635943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0176304,"threshold_uncertainty_score":0.7860845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01431969716842946,"score_gpt":0.2121548369460061,"score_spread":0.1978351397775766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}