{"id":"W2278623375","doi":"10.7150/ijbs.14951","title":"The Landscape of Pancreatic Cancer Therapeutic Resistance Mechanisms","year":2016,"lang":"en","type":"review","venue":"International Journal of Biological Sciences","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pancreas Centre (Canada)","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Pancreatic cancer; Disease; Bioinformatics; Medicine; Tumor microenvironment; Pancreatic ductal adenocarcinoma; Cancer; Cancer research; Somatic cell; Biology; Gene; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001862498,0.0001382887,0.001022002,0.0001363385,0.0000945618,0.00002775751,0.0009278021,0.0001512405,0.0003576989],"category_scores_gemma":[0.0006645666,0.00004560723,0.0003689498,0.0001841016,0.0007970345,0.00004011984,0.00007738119,0.0002373782,0.0000113949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001010808,"about_ca_system_score_gemma":0.0009093486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005414655,"about_ca_topic_score_gemma":0.000005734634,"domain_scores_codex":[0.9978626,0.0002605791,0.0007532052,0.0001555866,0.0007666002,0.0002014162],"domain_scores_gemma":[0.996398,0.002026671,0.0009291486,0.000100809,0.0004620469,0.00008327713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001776142,0.00007391885,0.002016926,0.0002216211,0.0008898101,0.00005530917,0.00001779513,5.164888e-8,0.00004577859,0.009575073,0.0004560507,0.98647],"study_design_scores_gemma":[0.0004548366,0.0009572494,0.001060332,0.01328157,0.0004436131,0.0003243732,0.0000568043,0.000004427929,0.00001585187,0.01141724,0.9718723,0.0001114286],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003512497,0.9942796,0.0002677593,0.001849317,0.0004843926,0.0001785262,0.00001962581,0.000003405876,0.002566116],"genre_scores_gemma":[0.002447216,0.995638,0.0004693221,0.00007176081,0.0003275151,0.00001584292,0.000001075188,0.000004218921,0.001025086],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9863586,"threshold_uncertainty_score":0.3916552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1549612591397564,"score_gpt":0.4676066326567239,"score_spread":0.3126453735169675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}