{"id":"W2278623375","doi":"10.7150/ijbs.14951","title":"The Landscape of Pancreatic Cancer Therapeutic Resistance Mechanisms","year":2016,"lang":"en","type":"review","venue":"International Journal of Biological Sciences","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pancreas Centre (Canada)","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Pancreatic cancer; Disease; Bioinformatics; Medicine; Tumor microenvironment; Pancreatic ductal adenocarcinoma; Cancer; Cancer research; Somatic cell; Biology; Gene; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000664783,0.000597917,0.001110311,0.001790913,0.0002881638,0.001112266,0.0007053458,0.0009892649,0.002146319],"category_scores_gemma":[0.0007051717,0.0002319136,0.0004123444,0.001331333,0.0005796617,0.00138502,0.0006833887,0.001602437,0.001045281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006187833,"about_ca_system_score_gemma":0.00094489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006105233,"about_ca_topic_score_gemma":0.001197393,"domain_scores_codex":[0.999797,0.00004129467,0.00002844989,0.00003632881,0.0000733928,0.00002341439],"domain_scores_gemma":[0.9996792,0.0001429534,0.00004560951,0.00001063984,0.00009233905,0.00002922047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006562522,0.00006627302,0.0002960296,0.01201764,0.00005864854,0.0002771317,0.00008712628,0.0003533934,0.001965603,0.005116757,0.01748286,0.9622129],"study_design_scores_gemma":[0.00001787572,0.0001678118,0.001345493,0.003693057,0.00009280485,0.002414895,0.0001221104,0.0001604124,0.0009482774,0.002903612,0.9881091,0.00002458495],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001682939,0.9984596,0.00009745993,0.0004442403,0.00008866908,0.000003259168,0.000009193674,0.000006790015,0.000722579],"genre_scores_gemma":[0.001103508,0.9981672,0.0001262603,0.000175552,0.0001126552,0.000005120442,0.00001604445,0.000001046793,0.0002926203],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002146319,"threshold_uncertainty_score":0.007180214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1549612591397564,"score_gpt":0.4676066326567239,"score_spread":0.3126453735169675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}