{"id":"W2278666748","doi":"10.1038/srep21385","title":"A polyalanine peptide derived from polar fish with anti-infectious activities","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Fundação para a Ciência e a Tecnologia; Horizon 2020 Framework Programme; Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul; Ministerio de Economía y Competitividad; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Ministério da Educação e Ciência; National Institutes of Health; Ministério da Educação; European Commission; Fundação de Apoio à Pesquisa do Distrito Federal; Fundación Ramón Areces","keywords":"In silico; Bacteria; Peptide; Antimicrobial peptides; Microbiology; Biology; Pathogenic bacteria; Antimicrobial; Drug discovery; Biofilm; Gram-negative bacteria; Escherichia coli; Antibiotics; Antibiotic resistance; Bacterial cell structure; Chemistry; Computational biology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009064953,0.0002818078,0.000132159,0.0001183974,0.00009535151,0.0001711311,0.0001265602,0.0002844943,0.0008361214],"category_scores_gemma":[0.0001168024,0.00007417407,0.0001944461,0.00008437825,0.000181654,0.0001771761,0.0001784283,0.0003141527,0.0002835023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001216076,"about_ca_system_score_gemma":0.0001385588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001710164,"about_ca_topic_score_gemma":0.0001905034,"domain_scores_codex":[0.9999648,0.000006673087,0.000002961938,0.000008161874,0.000009189007,0.000008200988],"domain_scores_gemma":[0.9999493,0.00001069279,0.00001451516,0.000002953802,0.000007748042,0.00001477873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001063699,0.00001144919,0.0001170854,0.00005496537,0.000002772485,0.00009546746,0.000005933589,0.0001318654,0.9972994,0.00007749328,0.00001555212,0.0020816],"study_design_scores_gemma":[0.00003125272,0.001108922,0.002608061,0.00001170007,0.00002702645,0.000763668,0.00001693761,0.0005799762,0.9903814,0.00007189807,0.004391146,0.000007910807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914415,0.001892141,0.004427294,0.0001294523,0.00003886178,0.00005103346,0.0001710582,0.00002208019,0.001826576],"genre_scores_gemma":[0.9894219,0.001216894,0.006900479,0.0001032904,0.00001497472,0.00003329461,0.0002524549,0.000007655359,0.002048954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008361214,"threshold_uncertainty_score":0.002797127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0065287090121818,"score_gpt":0.1966400488207636,"score_spread":0.1901113398085818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}