{"id":"W2279038813","doi":"","title":"Counterpoint: From animal models to prevention of colon cancer. Criteria for proceeding from preclinical studies and choice of models for prevention studies.","year":2003,"lang":"en","type":"article","venue":"PubMed","topic":"Nutrition, Genetics, and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Azoxymethane; Colorectal cancer; Cancer; Medicine; Cancer prevention; Carcinogenesis; Internal medicine; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002422554,0.0001242154,0.0002952681,0.00002814893,0.00004613119,0.000009648207,0.00007043857,0.00008214074,0.000001323893],"category_scores_gemma":[0.0003255088,0.0001269916,0.0001025239,0.00003596066,0.00006782851,0.00001589349,0.00004842489,0.00002008519,2.223361e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002109398,"about_ca_system_score_gemma":0.00004077809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002689308,"about_ca_topic_score_gemma":0.00008699213,"domain_scores_codex":[0.9989588,0.00003823442,0.0003785537,0.0003591088,0.00008851347,0.0001767746],"domain_scores_gemma":[0.9990804,0.00007728688,0.0001818333,0.0001207451,0.0004616503,0.00007811098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02649897,0.004361191,0.02350337,0.008303448,0.009142002,6.938394e-7,0.006169166,0.003822825,0.823713,0.002739837,0.02730829,0.06443723],"study_design_scores_gemma":[0.01379271,0.002860716,0.01808681,0.0007066926,0.001692152,5.819199e-7,0.004131614,0.006232768,0.6627519,0.2871687,0.001715276,0.0008601937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9620994,0.0189713,0.0159269,0.00007229402,0.0001782694,0.002046877,0.0006810422,0.000005094346,0.00001887167],"genre_scores_gemma":[0.9875511,0.001631952,0.006526665,0.00004817841,0.0002172819,0.003836021,0.000105155,0.00001654285,0.0000671145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2844288,"threshold_uncertainty_score":0.5178566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1789162979178427,"score_gpt":0.4052946888673626,"score_spread":0.22637839094952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}