{"id":"W2279285463","doi":"10.1016/j.tibtech.2016.01.005","title":"Biomedical Potential of mTOR Modulation by Nanoparticles","year":2016,"lang":"en","type":"article","venue":"Trends in biotechnology","topic":"Electrochemical sensors and biosensors","field":"Engineering","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"Jewish General Hospital; McGill University","funders":"Canadian Institutes of Health Research; Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja; Deutsche Forschungsgemeinschaft","keywords":"Modulation (music); Nanotechnology; Nanoparticle; PI3K/AKT/mTOR pathway; Chemistry; Computational biology; Biology; Materials science; Biochemistry; Physics; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003433447,0.00007576272,0.0001290432,0.0001963965,0.000006757301,0.000001375661,0.00009665453,0.0002968998,0.00007275766],"category_scores_gemma":[0.00001576598,0.00005221934,0.00002660054,0.0003252782,0.0001418529,0.0000224111,0.00001764046,0.00007852774,0.000009251028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003218697,"about_ca_system_score_gemma":0.000001410226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000757711,"about_ca_topic_score_gemma":0.000004932266,"domain_scores_codex":[0.9994072,0.000007598361,0.0001891141,0.000116852,0.00007090086,0.0002083777],"domain_scores_gemma":[0.9998158,0.00001437273,0.00001931562,0.000118359,0.00000615761,0.00002596847],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006961687,0.00002473531,0.00009079764,0.000003062428,0.000005814972,0.000001745751,0.000003468645,0.00001228161,0.8490841,0.0002424139,0.0007846045,0.14974],"study_design_scores_gemma":[0.0003246681,0.00006933967,0.0007158936,0.00001018035,0.000002521665,0.000004564109,0.0000039636,0.002611112,0.9942115,0.0003819264,0.001587624,0.00007670639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972824,0.0001219529,0.0006213903,0.001620695,0.00006200375,0.00001908197,0.00001199536,0.0001907359,0.00006968873],"genre_scores_gemma":[0.9994309,0.00008322931,0.0003856071,0.000005764623,0.0000171599,0.000002252256,0.000005477901,0.000009288021,0.00006030269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1496633,"threshold_uncertainty_score":0.2289963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004925244820767944,"score_gpt":0.2056577051912036,"score_spread":0.2007324603704356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}