{"id":"W2279694713","doi":"10.1128/aac.02328-15","title":"Identification of Synthetic and Natural Host Defense Peptides with Leishmanicidal Activity","year":2016,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research","keywords":"Identification (biology); Host (biology); Computational biology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001221524,0.0001314949,0.0002555288,0.00006259933,0.00008200404,0.00002596976,0.00004813597,0.0000413639,0.00002219656],"category_scores_gemma":[0.0000287818,0.00007480041,0.00003848945,0.00007187077,0.0003377287,0.0001280207,0.00003346286,0.00006650172,0.000003445833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002046656,"about_ca_system_score_gemma":0.00002215629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004552269,"about_ca_topic_score_gemma":0.00002319744,"domain_scores_codex":[0.9992239,0.00002553788,0.0001510311,0.0002583926,0.0001568458,0.0001843282],"domain_scores_gemma":[0.9995214,0.00004961108,0.00009568718,0.0001736603,0.0001004965,0.00005909757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007691314,0.0001566679,0.1113886,0.0001157095,0.000174385,0.000009130657,0.0002856692,2.353322e-8,0.8647377,0.00003811955,0.001511361,0.02081354],"study_design_scores_gemma":[0.002027465,0.0002158628,0.6524552,0.0001901084,0.00003812001,0.00007339187,0.0000409785,0.00001117211,0.3440512,0.00001269877,0.0007774545,0.0001063939],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923863,0.00005511464,0.0000733367,0.007081414,0.00002697234,0.0002680238,0.00001052116,0.00001865345,0.00007970024],"genre_scores_gemma":[0.9963387,0.002219076,0.00008762641,0.0004390905,0.00003596857,0.000004437563,0.000001036931,0.00001973457,0.0008543863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5410666,"threshold_uncertainty_score":0.3050272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01270945742598738,"score_gpt":0.2668510938500636,"score_spread":0.2541416364240762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}