{"id":"W2280074200","doi":"10.1007/s12026-015-8756-8","title":"Increased expression of long noncoding RNAs LOC100652951 and LOC100506036 in T cells from patients with rheumatoid arthritis facilitates the inflammatory responses","year":2015,"lang":"en","type":"article","venue":"Immunologic Research","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":false,"ca_institutions":"Public Health Ontario; University of Toronto","funders":"Ministry of Science and Technology, Taiwan","keywords":"Jurkat cells; Ionomycin; Small interfering RNA; Molecular biology; Transfection; NFAT; Biology; Gene expression; Cell culture; Immunology; Cancer research; T cell; Cell biology; Transcription factor; Gene; Immune system; Intracellular; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001851623,0.0001815709,0.0002353929,0.000221495,0.000135738,0.00005777743,0.0004660791,0.0002451653,0.00002624371],"category_scores_gemma":[0.001079515,0.0001266183,0.00004062851,0.000309927,0.0006776705,0.00001680199,0.0006643838,0.0005354958,0.0000123036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008493344,"about_ca_system_score_gemma":0.0003696533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001001813,"about_ca_topic_score_gemma":0.0002861028,"domain_scores_codex":[0.9967476,0.001209999,0.0003352122,0.0004767582,0.0007209726,0.0005094411],"domain_scores_gemma":[0.9983076,0.0003107548,0.00009196746,0.0006528992,0.000520087,0.0001166354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002877818,0.000111788,0.01345048,0.00001577519,0.00004174886,0.00003603863,0.0003502188,0.00009920941,0.976559,0.000008205922,0.0001979228,0.006251726],"study_design_scores_gemma":[0.002677253,0.000996718,0.02485521,0.0002314671,0.000001722171,0.000005241201,0.001063819,0.00004282006,0.9687138,0.0001600986,0.001086237,0.0001656026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901314,0.008611175,0.0003352618,0.00007083995,0.00004343503,0.0006211082,0.00004745404,0.0000100545,0.0001293129],"genre_scores_gemma":[0.9962367,0.003254652,0.0002225574,0.00001286244,0.00001759909,0.00009038969,0.00006384003,0.00002441274,0.00007696253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01140474,"threshold_uncertainty_score":0.5163346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02549956360992009,"score_gpt":0.2871088771718561,"score_spread":0.261609313561936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}