{"id":"W2280099094","doi":"10.1172/jci.insight.85841","title":"Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype","year":2016,"lang":"en","type":"article","venue":"JCI Insight","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":454,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Moonshot Research and Development Program; National Human Genome Research Institute; Rose Foundation for Communities and the Environment; University of Texas MD Anderson Cancer Center; National Cancer Institute; National Institutes of Health; Dr. Marnie Rose Foundation","keywords":"Microglia; Immune system; Phenotype; Integrin alpha M; Flow cytometry; Biology; Innate immune system; Myeloid-derived Suppressor Cell; Myeloid; Immunology; Mass cytometry; Macrophage; Cancer research; Inflammation; Suppressor; Gene; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002959963,0.000410722,0.0002664456,0.0009468839,0.0003021968,0.0003773714,0.00009742659,0.0002000854,0.002258616],"category_scores_gemma":[0.0002091127,0.0001446976,0.0001327496,0.0004842542,0.0003538324,0.0003264149,0.0003966052,0.0003049213,0.0007957125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000158888,"about_ca_system_score_gemma":0.0001655588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004646028,"about_ca_topic_score_gemma":0.001195742,"domain_scores_codex":[0.9998432,0.00002576397,0.00001358328,0.00003496079,0.00003646733,0.00004600157],"domain_scores_gemma":[0.9998759,0.00001525359,0.00002807575,0.00001937124,0.00003121335,0.0000300487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006761132,0.00004533397,0.02745561,0.0002532506,0.00002440254,0.0007149568,0.0006052025,0.0001370691,0.9534659,0.001567743,0.0003705074,0.01468398],"study_design_scores_gemma":[0.00009006682,0.001695687,0.3193175,0.000203731,0.0001349483,0.01653229,0.003556704,0.003273073,0.5842507,0.005970671,0.06490748,0.00006711683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853836,0.001307156,0.005993064,0.00007491613,0.00001903618,0.00008893033,0.001112172,0.0002118402,0.005809351],"genre_scores_gemma":[0.9917161,0.0005940035,0.004089167,0.00006334537,0.00001693362,0.00007627826,0.0006466451,0.0000330761,0.002764444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002258616,"threshold_uncertainty_score":0.007555842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009151921701594656,"score_gpt":0.2245010686313836,"score_spread":0.215349146929789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}