{"id":"W2280229941","doi":"10.71781/30657","title":"Systems biology of the human MHC class I immunopeptidome","year":2013,"lang":"en","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Canada Research Chairs; Pfizer","keywords":"Class (philosophy); Computational biology; MHC class I; Biology; Major histocompatibility complex; Computer science; Chemistry; Genetics; Artificial intelligence; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003934075,0.0002991716,0.0003265709,0.0002576785,0.0003904073,0.001106833,0.0003635311,0.0005042629,0.001794512],"category_scores_gemma":[0.0004282966,0.000211136,0.0003770088,0.0001647024,0.0007019539,0.0006102031,0.0004214501,0.0005949266,0.000471355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001249573,"about_ca_system_score_gemma":0.0004892572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001020619,"about_ca_topic_score_gemma":0.0006903892,"domain_scores_codex":[0.9997384,0.00006993422,0.000009876183,0.0001015094,0.0000507025,0.00002958545],"domain_scores_gemma":[0.9998062,0.00008961212,0.00002645551,0.00002823322,0.00002901933,0.00002052716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001198044,0.00003688862,0.001233297,0.000383892,0.0000486115,0.0001635257,0.0002769156,0.00535455,0.9277214,0.04162801,0.0004483267,0.02258487],"study_design_scores_gemma":[0.0001058042,0.001220179,0.01493178,0.0001118731,0.0001535742,0.001664637,0.0004346317,0.08951806,0.7435578,0.05663015,0.09156386,0.0001077058],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5399693,0.02557344,0.4030047,0.002300686,0.0005395098,0.0002971292,0.0005891266,0.0008116971,0.02691451],"genre_scores_gemma":[0.9073783,0.004646183,0.07946458,0.000313515,0.0000771346,0.0002024222,0.0004366394,0.00003768041,0.007443474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001794512,"threshold_uncertainty_score":0.009066284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005396652240589217,"score_gpt":0.1775710647658987,"score_spread":0.1721744125253095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}