{"id":"W2280499497","doi":"10.1097/mol.0000000000000273","title":"AMP-activated protein kinase and its multifaceted regulation of hepatic metabolism","year":2016,"lang":"en","type":"review","venue":"Current Opinion in Lipidology","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Protein kinase A; AMP-activated protein kinase; Cell biology; Chemistry; Kinase; Biology; AMPK","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004227305,0.0009280196,0.001264005,0.001711074,0.000260981,0.001167906,0.0008269209,0.0009758798,0.003749553],"category_scores_gemma":[0.0004218246,0.0002180318,0.0003602511,0.001936391,0.0004649007,0.001300476,0.0008486672,0.001514592,0.003320537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005624954,"about_ca_system_score_gemma":0.0009957047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004679606,"about_ca_topic_score_gemma":0.0006888837,"domain_scores_codex":[0.9998605,0.00001970125,0.00002502945,0.00002793777,0.00004861762,0.0000181459],"domain_scores_gemma":[0.9998057,0.00005835475,0.00004886353,0.000006389361,0.00005096183,0.00002965024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001151761,0.00005380067,0.0002527609,0.01813625,0.00009956401,0.0005226132,0.00008072133,0.0004106199,0.005861082,0.004931032,0.02914762,0.9403887],"study_design_scores_gemma":[0.0000134019,0.00007439066,0.001106587,0.002864571,0.00009960221,0.002698205,0.00007833643,0.00009001725,0.001209749,0.00252606,0.989216,0.00002315245],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000120456,0.9985625,0.0001180548,0.0002869319,0.0002371211,0.000003279556,0.00001851511,0.000008193009,0.0006449211],"genre_scores_gemma":[0.0006544055,0.9984268,0.0001353672,0.00010787,0.0002728632,0.000003574811,0.00003077995,0.000001234802,0.0003671358],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003749553,"threshold_uncertainty_score":0.0125435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07911385511935275,"score_gpt":0.3727835635285333,"score_spread":0.2936697084091805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}