{"id":"W2280540363","doi":"10.2174/1570162x13666150827093449","title":"Role of HIV-1 Envelope Glycoproteins Conformation and Accessory Proteins on ADCC Responses","year":2015,"lang":"en","type":"article","venue":"Current HIV Research","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Antibody-dependent cell-mediated cytotoxicity; Epitope; Glycoprotein; Effector; Virology; Biology; Antibody; Human immunodeficiency virus (HIV); Vaccine trial; Immunology; Monoclonal antibody; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00150337,0.0001561912,0.0002400364,0.0004849764,0.0002370329,0.00003117313,0.0003118204,0.000136142,0.0003042888],"category_scores_gemma":[0.0008729988,0.000121683,0.00004327135,0.0002848585,0.0005595389,0.0001869838,0.0002744668,0.0006476108,0.004269788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001177791,"about_ca_system_score_gemma":0.0005134034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006916941,"about_ca_topic_score_gemma":0.00001483034,"domain_scores_codex":[0.9976745,0.0008322056,0.0002899216,0.0003028945,0.0002998462,0.0006006682],"domain_scores_gemma":[0.9986348,0.00031147,0.0000734416,0.0003796355,0.0004599516,0.0001407108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0160406,0.003378494,0.04577458,0.0005738037,0.0004831141,0.0000339298,0.01088107,0.000008648917,0.2378071,0.009128489,0.1013232,0.574567],"study_design_scores_gemma":[0.007089182,0.002747724,0.04002872,0.0003447094,0.00001732027,0.00003343739,0.002512781,0.00002512034,0.3235339,0.001157759,0.622181,0.0003283807],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749919,0.01323655,0.00004118416,0.0006816451,0.0001218834,0.001709157,0.0005119363,0.00004996667,0.008655779],"genre_scores_gemma":[0.9956543,0.0005429269,0.00004733414,0.000005354736,0.00003298665,0.0002884189,0.0004431646,0.00001364428,0.002971889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5742387,"threshold_uncertainty_score":0.9965055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1223153538722881,"score_gpt":0.3891224774182779,"score_spread":0.2668071235459898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}