{"id":"W2280543337","doi":"10.2174/1568026615666150413154038","title":"Outlook for Aptamers After Twenty Five Years","year":2015,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Aptamer; Nanotechnology; Computational biology; Computer science; Biology; Molecular biology; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001017055,0.0009619151,0.0007154073,0.001486551,0.0003487759,0.001103932,0.0006111909,0.001777927,0.007692425],"category_scores_gemma":[0.0009121004,0.0002967168,0.0004976523,0.001143383,0.0004861314,0.002024735,0.00101036,0.00237572,0.005297387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007671239,"about_ca_system_score_gemma":0.0008762656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005377067,"about_ca_topic_score_gemma":0.0008827342,"domain_scores_codex":[0.9997277,0.00004234623,0.00003279999,0.0000551572,0.0001030357,0.00003894036],"domain_scores_gemma":[0.9996413,0.0001443351,0.0000430557,0.00001393088,0.0001074761,0.00004993124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007699731,0.00007424168,0.000173354,0.007607146,0.00004546261,0.0003298296,0.0001196662,0.000371023,0.005131832,0.01603496,0.06538767,0.9046479],"study_design_scores_gemma":[0.000005214042,0.00004743265,0.0001492262,0.000748697,0.00001454378,0.0005530862,0.00002495906,0.00003213778,0.0005045369,0.001788593,0.9961241,0.00000752239],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002666309,0.9930753,0.0004226721,0.001188782,0.001091375,0.000008192478,0.00003382269,0.00002115093,0.003892216],"genre_scores_gemma":[0.002107742,0.987755,0.0006097461,0.00171936,0.0005863645,0.00002003231,0.00008144366,0.0000058578,0.007114426],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007692425,"threshold_uncertainty_score":0.02573371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04072924697461636,"score_gpt":0.3877966872424451,"score_spread":0.3470674402678287,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}