{"id":"W2280725493","doi":"10.3389/fonc.2016.00037","title":"Glycosylated Notch and Cancer","year":2016,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Science and Engineering Research Board; Cancer Research UK","keywords":"Notch signaling pathway; Glycosylation; Notch proteins; Carcinogenesis; Fucose; Biology; Cell fate determination; Cell biology; Signal transduction; Metastasis; Cancer; Cancer research; Computational biology; Chemistry; Glycoprotein; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001735065,0.0002403643,0.0007388325,0.0001289421,0.00003634455,0.000004261314,0.0001532394,0.00102546,0.00002747517],"category_scores_gemma":[0.00003153574,0.0001800491,0.00009018017,0.00009546529,0.0001562127,0.000001915566,0.0001253861,0.0001396801,0.00001247773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001401804,"about_ca_system_score_gemma":0.0003993679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005517176,"about_ca_topic_score_gemma":0.00003434915,"domain_scores_codex":[0.9987516,0.0001812977,0.0003194039,0.000455952,0.00003873604,0.0002530403],"domain_scores_gemma":[0.9995781,0.0000180428,0.0001629165,0.0001666608,0.00002003109,0.00005421766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003110285,0.00001591978,0.0004173924,0.0003448686,0.0001002279,0.000006674927,0.000007410903,1.415475e-7,0.00008541633,0.000006267829,0.0154357,0.9835489],"study_design_scores_gemma":[0.0003259925,0.0001083587,0.00008224582,0.0005461653,0.00005628253,0.00003579633,0.000004130333,7.807577e-7,0.00007366081,0.000066924,0.9984639,0.0002358032],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001599381,0.9968696,0.0001591024,0.00007495595,0.001494017,0.000318817,0.00003995731,0.00000694583,0.0008767116],"genre_scores_gemma":[0.00003883831,0.9960578,0.000988393,0.00008756366,0.0002103413,0.0001413002,0.0002743839,0.00002404162,0.002177322],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9833131,"threshold_uncertainty_score":0.7909288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01560318818530696,"score_gpt":0.3382214088895323,"score_spread":0.3226182207042254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}