{"id":"W2280725493","doi":"10.3389/fonc.2016.00037","title":"Glycosylated Notch and Cancer","year":2016,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Science and Engineering Research Board; Cancer Research UK","keywords":"Notch signaling pathway; Glycosylation; Notch proteins; Carcinogenesis; Fucose; Biology; Cell fate determination; Cell biology; Signal transduction; Metastasis; Cancer; Cancer research; Computational biology; Chemistry; Glycoprotein; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000264192,0.0004594434,0.0005306395,0.001012022,0.0002040112,0.0007943882,0.0004423677,0.0008252996,0.003592978],"category_scores_gemma":[0.0003609121,0.0001284708,0.0002199282,0.001199428,0.0003378564,0.0008124232,0.0006843148,0.001130003,0.001776915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006189201,"about_ca_system_score_gemma":0.0007975937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008816927,"about_ca_topic_score_gemma":0.001278588,"domain_scores_codex":[0.9998846,0.00001572459,0.00001587964,0.00001958439,0.0000502309,0.00001407408],"domain_scores_gemma":[0.9999167,0.00002567087,0.00001426387,0.000004034859,0.00002601745,0.0000132962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009629955,0.00003516475,0.0002570433,0.007944483,0.00006318135,0.0003652939,0.00007433807,0.0002837623,0.003243377,0.008490666,0.03877054,0.9403759],"study_design_scores_gemma":[0.000006502324,0.00002793825,0.0003867993,0.00110505,0.0000330201,0.00150694,0.00003339153,0.00003751236,0.0005656403,0.002050934,0.9942383,0.000007883652],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001782565,0.9977442,0.00008611547,0.0003026432,0.0002224762,0.000002241155,0.0000176427,0.000006662486,0.001439729],"genre_scores_gemma":[0.001486742,0.9964646,0.0001170529,0.000253954,0.0001795339,0.000002705513,0.00003988992,0.000001705907,0.001453829],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003592978,"threshold_uncertainty_score":0.01201969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01560318818530696,"score_gpt":0.3382214088895323,"score_spread":0.3226182207042254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}