{"id":"W2280833244","doi":"10.1002/jbmr.2816","title":"Small Players Ruling the Hard Game: siRNA in Bone Regeneration","year":2016,"lang":"en","type":"review","venue":"Journal of Bone and Mineral Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Children's Hospital","funders":"","keywords":"Regeneration (biology); Small interfering RNA; Gene silencing; Medicine; Bioinformatics; Biology; RNA; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002211159,0.0001867692,0.000624758,0.0003178267,0.00006995981,0.00008231749,0.0002228659,0.0002721777,0.00001277328],"category_scores_gemma":[0.0003755415,0.0001000913,0.0002722758,0.0001490236,0.0001118147,0.00000913998,0.0001508869,0.0006259779,0.000009923265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004371397,"about_ca_system_score_gemma":0.0004316324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002385687,"about_ca_topic_score_gemma":0.00008644642,"domain_scores_codex":[0.9980576,0.0003663787,0.0006981305,0.0002358645,0.0003146487,0.000327402],"domain_scores_gemma":[0.9989231,0.00009918911,0.0003084319,0.000241644,0.0003249927,0.0001027058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001302888,0.00004025667,0.00001153655,0.0006353048,0.0001167732,0.0001472413,0.00005023772,0.000003656098,0.04378429,0.00002571013,0.01230419,0.9427505],"study_design_scores_gemma":[0.0003623153,0.0005298767,0.0000171723,0.003885224,0.00004368293,0.0005146246,0.00004507783,0.000006068141,0.0009184158,0.00003996563,0.9934893,0.0001482592],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04442537,0.9547129,0.00004972766,0.0002974899,0.0001353996,0.0001840786,0.000009418063,7.853371e-7,0.0001848878],"genre_scores_gemma":[0.002635884,0.9901983,0.00008176425,0.00004637087,0.001066512,0.00001292742,0.00001701931,0.00002155922,0.005919669],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9811851,"threshold_uncertainty_score":0.4081603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1488801672694759,"score_gpt":0.3930253073846513,"score_spread":0.2441451401151754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}