{"id":"W2280879448","doi":"10.1379/1466-1268(2001)006<0136:tnmiat>2.0.co;2","title":"The nuclear matrix is a thermolabile cellular structure","year":2001,"lang":"en","type":"article","venue":"Cell Stress and Chaperones","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Thermolabile; Nuclear matrix; Denaturation (fissile materials); Biophysics; Chemistry; Heat shock protein; Nuclear protein; Nucleus; Differential scanning calorimetry; Hyperchromicity; Biochemistry; Biology; Chromatin; DNA; Nuclear chemistry; Cell biology; Enzyme; Thermodynamics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001791796,0.0003698582,0.0002626011,0.0003294327,0.0006985052,0.0008875719,0.0002754151,0.0003338993,0.00124708],"category_scores_gemma":[0.0002166035,0.0002230615,0.0001865247,0.0002687248,0.0008202055,0.001035929,0.0005543803,0.0005767106,0.0008500168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004072486,"about_ca_system_score_gemma":0.0004124918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005611518,"about_ca_topic_score_gemma":0.0009827357,"domain_scores_codex":[0.9998921,0.00001837737,0.00000578021,0.00003222445,0.00003388413,0.00001769674],"domain_scores_gemma":[0.9996294,0.00004737412,0.00009218839,0.00006505598,0.00006778487,0.00009813731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000555329,0.00000682327,0.0002775684,0.00008507483,0.000008829613,0.0001473394,0.00005575067,0.000107014,0.9898849,0.004216774,0.000300287,0.004854075],"study_design_scores_gemma":[0.00002144796,0.0003185986,0.01199028,0.00007467536,0.00005503906,0.002680851,0.0005295721,0.0009527081,0.8839027,0.00688048,0.09254028,0.00005326831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8493081,0.04491636,0.08090623,0.002346889,0.0009964139,0.00007851684,0.001280562,0.001216602,0.01895032],"genre_scores_gemma":[0.9651659,0.008478644,0.01263817,0.0001991877,0.0001514039,0.00004066723,0.0008660018,0.00008464614,0.01237535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00124708,"threshold_uncertainty_score":0.004171908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006222878694723248,"score_gpt":0.2389503502140897,"score_spread":0.2327274715193665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}