{"id":"W2280948563","doi":"10.1074/mcp.m115.053298","title":"Comparative Phosphoproteomics Analysis of VEGF and Angiopoietin-1 Signaling Reveals ZO-1 as a Critical Regulator of Endothelial Cell Proliferation","year":2016,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Angiogenesis; Cell biology; Signal transduction; Regulator; Angiopoietin; Vascular endothelial growth factor; Phosphorylation; Phosphoproteomics; Biology; Cell signaling; Chemistry; Protein kinase A; Cancer research; Protein phosphorylation; VEGF receptors; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001108309,0.0003199769,0.000210247,0.0003973308,0.0002063233,0.0002251562,0.0001877297,0.0002275507,0.000765544],"category_scores_gemma":[0.00008709218,0.0001201789,0.0002641653,0.0003129919,0.0001514548,0.0003649823,0.0001868739,0.0002905069,0.0001388122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001897932,"about_ca_system_score_gemma":0.0001574646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006086804,"about_ca_topic_score_gemma":0.0008088347,"domain_scores_codex":[0.9999332,0.000006346999,0.000003377936,0.00002284759,0.00001791728,0.00001631725],"domain_scores_gemma":[0.9999588,0.000004441313,0.00001376198,0.00000252613,0.000006487105,0.0000140986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000686623,0.000005642308,0.0002984754,0.00003069948,0.000006629567,0.00002197972,0.000007661655,0.00002552614,0.9987068,0.00005326217,0.00001627805,0.0007583025],"study_design_scores_gemma":[0.00002082817,0.0002048257,0.1196578,0.00001300411,0.000101985,0.0009920807,0.0000869085,0.003245024,0.8720201,0.0003502136,0.00329224,0.00001503952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915556,0.003050689,0.00388064,0.00009461462,0.00001570228,0.00001479353,0.000702114,0.00003033718,0.0006555563],"genre_scores_gemma":[0.9888228,0.001956631,0.00644793,0.00008220816,0.00001183494,0.00002819322,0.001447604,0.00001327857,0.001189645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000765544,"threshold_uncertainty_score":0.002560973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009920193625834139,"score_gpt":0.2581656300257293,"score_spread":0.2482454363998952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}