{"id":"W2281031962","doi":"10.1159/000442446","title":"Clinical Trial Risk in Chronic Obstructive Pulmonary Disease: The Effects of Drug Class and Inclusion Criteria","year":2015,"lang":"en","type":"article","venue":"Respiration","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Amorfix (Canada)","funders":"","keywords":"Medicine; Pulmonary disease; Drug; Clinical trial; Disease; Drug class; Respiratory disease; Randomized controlled trial; Internal medicine; Intensive care medicine; Lung; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001550203,0.0001626916,0.0003554856,0.0001533383,0.0001989691,0.00001681745,0.000149405,0.0001071194,0.00002002428],"category_scores_gemma":[0.002658158,0.0001181234,0.0001103549,0.0003023164,0.0003642772,0.0002009597,0.0009140149,0.0004148844,0.000006436822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000636259,"about_ca_system_score_gemma":0.0009706922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002086831,"about_ca_topic_score_gemma":0.00006835619,"domain_scores_codex":[0.9970351,0.001052011,0.0005636308,0.0004161202,0.0006839999,0.0002491491],"domain_scores_gemma":[0.9981208,0.0006812508,0.0002103699,0.0004700762,0.0001893223,0.0003281956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.1419988,0.001745883,0.321292,0.00284997,0.0001568324,0.0005921404,0.002831113,0.00008922718,0.008505434,0.0009706668,0.001168115,0.5177998],"study_design_scores_gemma":[0.02968428,0.0008250203,0.9481825,0.0002767067,0.0001624126,0.000007280335,0.0001381407,0.01252591,0.0003756208,0.00485726,0.002815474,0.0001494164],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893087,0.006988378,0.00003250446,0.0006471181,0.000404578,0.002079879,0.00002203842,0.00002258312,0.0004942054],"genre_scores_gemma":[0.9984673,0.0003172356,0.00004647798,0.00007545526,0.000785278,0.0001011395,0.00004090738,0.00002260656,0.0001435455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6268905,"threshold_uncertainty_score":0.4816931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03451740593275771,"score_gpt":0.3703405352210634,"score_spread":0.3358231292883057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}