{"id":"W2281171596","doi":"10.1016/j.cub.2015.12.030","title":"Gene Amplification: Trophoblast Giant Cells Use All the Tricks","year":2016,"lang":"en","type":"letter","venue":"Current Biology","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Biology; Gene duplication; Endoreduplication; Gene; Trophoblast; Genetics; Evolutionary biology; Cell biology; Placenta; Ploidy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001314278,0.0003207915,0.0004547307,0.0001077946,0.00007087176,0.00002813029,0.0003519225,0.0006813898,0.0001935954],"category_scores_gemma":[0.0003346163,0.0001632909,0.0002034911,0.00009643836,0.0002859466,0.00002452643,0.0001299924,0.001257277,0.0007835725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007672706,"about_ca_system_score_gemma":0.0001072408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003219808,"about_ca_topic_score_gemma":0.000001098713,"domain_scores_codex":[0.998265,0.0001753741,0.0003680032,0.0005151654,0.0001576554,0.000518829],"domain_scores_gemma":[0.997739,0.0009691774,0.0002310311,0.0008383456,0.000117109,0.0001054005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004110772,0.00003121618,0.0002689805,0.00004574602,0.0000769498,0.00005573288,0.00001916072,9.60214e-8,0.0018358,0.00004544628,0.9416793,0.05590045],"study_design_scores_gemma":[0.0006050814,0.0001876789,0.0006850264,0.0001292359,0.0002057769,0.00006812814,0.000001534564,0.000007834935,0.001231809,0.00009914986,0.9965619,0.0002168409],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001500714,0.01005431,0.009292452,0.9691585,0.006186409,0.001186702,0.001732813,0.0002153228,0.00067274],"genre_scores_gemma":[0.01369334,0.01229464,0.001035142,0.9073306,0.04419997,0.0003266047,0.0137449,0.0001765358,0.007198311],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.06182797,"threshold_uncertainty_score":0.9999945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07680710409020837,"score_gpt":0.311926263201602,"score_spread":0.2351191591113937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}