{"id":"W2281678685","doi":"10.1371/journal.pone.0149204","title":"Structural and Biochemical Insights into the Peptidoglycan Hydrolase Domain of FlgJ from Salmonella typhimurium","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Universities Space Research Association","keywords":"Peptidoglycan; Active site; Biochemistry; Hydrolase; Glycosidic bond; Glycoside hydrolase; Glycan; Residue (chemistry); Helix (gastropod); Biology; Enzyme; Protein structure; Chemistry; Stereochemistry; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003355265,0.00008045394,0.0000900781,0.0000157229,0.00004008311,0.000007277152,0.00008486106,0.00007555114,0.00002924842],"category_scores_gemma":[0.00004727987,0.00004732705,0.00002179514,0.0000358894,0.0001225193,0.000003985609,0.00006645563,0.00003653235,0.000004569842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005272132,"about_ca_system_score_gemma":0.00001269322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001290508,"about_ca_topic_score_gemma":0.000008272072,"domain_scores_codex":[0.9994647,0.00003604441,0.0001221571,0.0002045374,0.00009580974,0.00007675681],"domain_scores_gemma":[0.9996073,0.00001029747,0.00006146596,0.0002279529,0.00005150611,0.00004142775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007557355,0.00005043929,0.001652392,0.000009459106,0.00005871907,1.998753e-7,0.000210911,9.274488e-8,0.9975203,0.00004173606,0.0000835663,0.0002965934],"study_design_scores_gemma":[0.0003187023,0.00006663102,0.003895309,0.00002638203,0.00002220425,8.597e-7,0.00003184017,0.0000121775,0.9943959,0.0006041281,0.0005465058,0.00007932258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998269,0.0005444909,0.00004942233,0.0009392367,0.00003306529,0.00008381875,0.00001243299,0.0000072507,0.00006123289],"genre_scores_gemma":[0.9985635,0.0002658575,0.0004737201,0.0001015292,0.0002993341,0.000005921942,0.00007157106,0.00001038018,0.0002081382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00312438,"threshold_uncertainty_score":0.1929941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01117943438475838,"score_gpt":0.194990795212191,"score_spread":0.1838113608274326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}