{"id":"W2281678685","doi":"10.1371/journal.pone.0149204","title":"Structural and Biochemical Insights into the Peptidoglycan Hydrolase Domain of FlgJ from Salmonella typhimurium","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Universities Space Research Association","keywords":"Peptidoglycan; Active site; Biochemistry; Hydrolase; Glycosidic bond; Glycoside hydrolase; Glycan; Residue (chemistry); Helix (gastropod); Biology; Enzyme; Protein structure; Chemistry; Stereochemistry; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009226747,0.0003909731,0.0002568465,0.0001483081,0.0001453332,0.0002974651,0.0003021669,0.0003569073,0.0006295917],"category_scores_gemma":[0.000136848,0.000190869,0.0004061737,0.0001392829,0.0002050636,0.000193248,0.0002120727,0.0006007834,0.0002638532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004498363,"about_ca_system_score_gemma":0.0003419436,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003683279,"about_ca_topic_score_gemma":0.003638192,"domain_scores_codex":[0.9999582,0.000006300268,0.000003276588,0.000006875773,0.0000123267,0.00001314674],"domain_scores_gemma":[0.9999357,0.000009557384,0.00001561654,0.000003463304,0.000008989315,0.00002669295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00070412,0.0001507494,0.003149132,0.0002972788,0.00004045207,0.001252438,0.0001962204,0.003257624,0.9859152,0.0005190442,0.0004621355,0.004055658],"study_design_scores_gemma":[0.0005710262,0.003287596,0.1327459,0.0002293995,0.0004408359,0.006404416,0.002648502,0.06720831,0.7477589,0.001629861,0.03689453,0.000180839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965965,0.001232776,0.001004765,0.000160262,0.00002744215,0.00001189282,0.0002089754,0.00004455762,0.0007128693],"genre_scores_gemma":[0.9943053,0.0008596464,0.002653303,0.0001525042,0.00001318959,0.000008585644,0.001192223,0.00001570692,0.0007995918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003683279,"threshold_uncertainty_score":0.007323682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01117943438475838,"score_gpt":0.194990795212191,"score_spread":0.1838113608274326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}