{"id":"W2281769251","doi":"10.1021/acs.jnatprod.5b00227","title":"Dirchromones: Cytotoxic Organic Sulfur Compounds Isolated from <i>Dirca palustris</i>","year":2015,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Biological Activity of Diterpenoids and Biflavonoids","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Chicoutimi","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research","keywords":"Sulfur; Cytotoxic T cell; Stereochemistry; Chemistry; Biology; Organic chemistry; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004177723,0.0002250961,0.0003727039,0.00005358613,0.00006325389,0.00006219345,0.0004226535,0.0002441497,0.000014645],"category_scores_gemma":[0.0004864822,0.0001544892,0.0001349851,0.0002102073,0.000111092,0.00002697609,0.0001185871,0.0004949624,0.00001980734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004090734,"about_ca_system_score_gemma":0.0002192968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000184368,"about_ca_topic_score_gemma":0.00001378574,"domain_scores_codex":[0.9985304,0.0001414097,0.000424648,0.0003263195,0.0002970769,0.0002800862],"domain_scores_gemma":[0.998555,0.00002344794,0.0003344054,0.0002844471,0.0006115129,0.0001911845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004437179,0.0001731033,0.0005681358,0.000007141109,0.0001091493,0.00002987186,0.00004006662,0.000003680065,0.9795107,0.000002965225,0.01770023,0.001411231],"study_design_scores_gemma":[0.001714288,0.002216736,0.003122906,0.00003961115,0.00006307948,0.0002907114,0.00008685058,0.00003112719,0.9586121,0.0005336786,0.0329156,0.0003732478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896643,0.006434198,0.0001185419,0.00251094,0.001035995,0.0001193801,0.00001881949,0.00001271049,0.00008511398],"genre_scores_gemma":[0.9956759,0.0002805406,0.001022409,0.0004421939,0.00211553,7.623455e-7,0.00008445641,0.0000192315,0.0003589308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02089854,"threshold_uncertainty_score":0.6299886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0186776199967664,"score_gpt":0.2400711749128231,"score_spread":0.2213935549160568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}