{"id":"W2281951751","doi":"10.1159/000419801","title":"Tumor Cell Subpopulation Interactions Mediated by Transforming Growth Factor � May Contribute to Clonal Dominance of Metastatically Competent Cells in Primary Tumors","year":2015,"lang":"en","type":"book-chapter","venue":"","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; University of Toronto","funders":"","keywords":"Dominance (genetics); Primary (astronomy); Biology; Cancer research; Transforming growth factor; Tumor cells; Cell biology; Genetics; Gene; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001449519,0.0002344924,0.0002346572,0.00025882,0.0002808928,0.0007734447,0.0003469895,0.0002806112,0.003491593],"category_scores_gemma":[0.0001220331,0.0001832231,0.0002254458,0.0002315782,0.0002053639,0.000413759,0.0003849345,0.0008864479,0.001214411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004437687,"about_ca_system_score_gemma":0.0002156176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00053235,"about_ca_topic_score_gemma":0.001426111,"domain_scores_codex":[0.9999335,0.00000716109,0.000002273734,0.00001270589,0.00002981595,0.00001453762],"domain_scores_gemma":[0.9999406,0.00002753048,0.000006007412,0.000004681728,0.00001134363,0.000009881282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009793713,0.00005973055,0.0008813624,0.0001042798,0.000009481992,0.0006887019,0.0002750258,0.0005055364,0.8915561,0.02385771,0.005005234,0.07695897],"study_design_scores_gemma":[0.0000187573,0.0003439599,0.01048557,0.00006020382,0.00006369692,0.005101737,0.0003007295,0.005004468,0.7373627,0.01369502,0.2275303,0.00003280804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5270857,0.06877257,0.08837618,0.002718262,0.00118669,0.0001186196,0.0005948393,0.001244028,0.3099031],"genre_scores_gemma":[0.686368,0.02485361,0.02014667,0.0005325408,0.0003077854,0.0000666253,0.0004902012,0.000311765,0.2669228],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003491593,"threshold_uncertainty_score":0.01168048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04378340730407314,"score_gpt":0.3221529782172308,"score_spread":0.2783695709131576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}