{"id":"W2282226610","doi":"10.1039/c6cp00476h","title":"Combined probes of X-ray scattering and optical spectroscopy reveal how global conformational change is temporally and spatially linked to local structural perturbation in photoactive yellow protein","year":2016,"lang":"en","type":"article","venue":"Physical Chemistry Chemical Physics","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kensington Health","funders":"National Institute of General Medical Sciences; Engineering and Physical Sciences Research Council; National Institutes of Health","keywords":"Chromophore; Spectroscopy; Scattering; Chemistry; Absorption spectroscopy; Absorption (acoustics); Chemical physics; Conformational change; Molecular physics; Photochemistry; Ultrafast laser spectroscopy; Crystallography; Analytical Chemistry (journal); Materials science; Optics; Physics; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005218671,0.0002428777,0.0003253216,0.00001521733,0.00004244556,0.00005288431,0.0002210152,0.00009440236,0.00001273633],"category_scores_gemma":[0.0001935657,0.0001913602,0.00005680515,0.0002107237,0.0005680979,0.0002652969,0.0002351151,0.0001986205,0.000002783469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001540844,"about_ca_system_score_gemma":0.00006997039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000162389,"about_ca_topic_score_gemma":5.812589e-7,"domain_scores_codex":[0.9984021,0.00002692074,0.0002172507,0.0004918877,0.0004956797,0.0003661912],"domain_scores_gemma":[0.9992413,0.0001538365,0.00009021793,0.000178328,0.00009111246,0.0002452211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002661229,0.0001211654,0.0004608976,0.0001595771,0.000006363681,0.000001509698,0.0003668464,0.000002502551,0.9967191,0.0001668116,0.00001261954,0.001716457],"study_design_scores_gemma":[0.000949421,0.0001233497,0.001161291,0.0001213499,0.000005684558,0.000001982924,0.00002530123,0.003925934,0.9891547,0.004291109,0.000004880116,0.0002349807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971952,0.0000034069,0.0007592458,0.001103,0.00001265644,0.0005560203,0.0001481537,0.00002171098,0.0002006507],"genre_scores_gemma":[0.9990211,0.000003356955,0.0005262927,0.0001174257,0.0001842854,0.00009038037,0.0000130936,0.00001591051,0.00002818306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007564411,"threshold_uncertainty_score":0.7803442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0273017850325446,"score_gpt":0.28299704298502,"score_spread":0.2556952579524754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}