{"id":"W2282763333","doi":"10.2174/1389450116666151001112710","title":"Sphingosine-1-Phosphate Receptors in the Central Nervous and Immune Systems","year":2015,"lang":"en","type":"review","venue":"Current Drug Targets","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Sphingosine-1-phosphate; Receptor; Immune system; Central nervous system; Sphingosine-1-phosphate receptor; Sphingosine; Neuroscience; Biology; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001001648,0.0005016204,0.001065002,0.00009230178,0.00009088249,0.0001178625,0.0005688217,0.0002333928,0.000005047439],"category_scores_gemma":[0.0001100341,0.0003350804,0.0002700829,0.0002025415,0.00007835779,0.0000072257,0.0002019971,0.0004237752,0.00001283128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003478548,"about_ca_system_score_gemma":0.0002213152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007763256,"about_ca_topic_score_gemma":0.000006149122,"domain_scores_codex":[0.9975407,0.0003988679,0.000663491,0.0005810363,0.0002568031,0.0005591511],"domain_scores_gemma":[0.9988918,0.00003067559,0.0003292399,0.000536644,0.00006382733,0.0001477831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001868608,0.000126101,0.00006327405,0.007521611,0.0001151581,0.00001272925,0.0006603848,0.00002042525,0.00003817243,0.0002007545,0.01692416,0.9742985],"study_design_scores_gemma":[0.0002883853,0.00001718959,0.0000136097,0.001967346,0.000187073,0.00003359093,0.00008772749,0.00001112656,0.00002695761,0.00001126417,0.9969671,0.0003886189],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007654305,0.9934334,0.00002080715,0.00001676357,0.004779067,0.0008137845,0.0000495167,0.00001467287,0.0001065521],"genre_scores_gemma":[0.0008929907,0.9964603,0.00001969805,0.00001820529,0.001497373,0.0001153297,0.0008079201,0.00005692954,0.0001312577],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9800429,"threshold_uncertainty_score":0.9999101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03322532400341214,"score_gpt":0.3100523081428299,"score_spread":0.2768269841394177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}