{"id":"W2283150954","doi":"10.1021/acs.nanolett.5b04877","title":"Potentiating Cancer Immunotherapy Using Papaya Mosaic Virus-Derived Nanoparticles","year":2016,"lang":"en","type":"article","venue":"Nano Letters","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Fondation Jean-Louis Lévesque; Canadian Institute for Advanced Research","keywords":"Immune system; Immunotherapy; Adjuvant; Cancer immunotherapy; Chemokine; Oncolytic virus; Cancer vaccine; Cancer research; Immunology; Immune checkpoint; CD8; Medicine; Cancer; Dendritic cell; T cell; Vaccination; Melanoma; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008574705,0.0002073969,0.0001536711,0.00009735852,0.00004951988,0.0001498237,0.0000681202,0.0001930649,0.0004201064],"category_scores_gemma":[0.00006998253,0.00004996277,0.0001239,0.00004374059,0.00009698251,0.0001218326,0.000129013,0.0002640875,0.0001404908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008206186,"about_ca_system_score_gemma":0.00008829618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000105811,"about_ca_topic_score_gemma":0.000148203,"domain_scores_codex":[0.9999584,0.00001054644,0.000001992882,0.000008809788,0.00001103414,0.000009109494],"domain_scores_gemma":[0.999975,0.000009840262,0.000005587158,0.000002428872,0.000003274994,0.000003965866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000355025,0.00002257901,0.00005819659,0.00002970444,0.000002123807,0.00002483473,0.000005130208,0.0001839985,0.9965141,0.00006887737,0.00002529419,0.003029617],"study_design_scores_gemma":[0.00001271463,0.0004548366,0.0005793921,0.000005084091,0.00001358938,0.0001553947,0.000006433246,0.002097959,0.994112,0.000085805,0.002474463,0.000002335691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981914,0.004373068,0.01055424,0.0001625302,0.0000607455,0.00005062448,0.00004318849,0.0001219782,0.002719654],"genre_scores_gemma":[0.9925174,0.001594216,0.004592343,0.0000464697,0.00002557195,0.00002624629,0.00004033936,0.000009939375,0.001147498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004201064,"threshold_uncertainty_score":0.001405358,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01655214074274477,"score_gpt":0.2517663593912247,"score_spread":0.2352142186484799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}