{"id":"W2283193718","doi":"10.1101/pdb.prot078329","title":"Tissue Dissociation for Metastasis Studies","year":2016,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Viability assay; Cell sorting; Dissociation (chemistry); Trypan blue; Metastasis; Cell; Chemistry; Suspension culture; Suspension (topology); Staining; Fluorescence; Biophysics; Cell biology; Pathology; Cell culture; Cancer research; Molecular biology; Biology; Medicine; Biochemistry; Cancer; Mathematics; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001896401,0.000104613,0.0001339941,0.0000197001,0.00007499176,0.00002379517,0.0001164963,0.00006008172,0.000005101489],"category_scores_gemma":[0.0005515134,0.00008092205,0.00006245921,0.00003224024,0.00003301793,0.00000339263,0.00007958209,0.00001779196,0.000008491741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004920759,"about_ca_system_score_gemma":0.00005651165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003113016,"about_ca_topic_score_gemma":0.00001343931,"domain_scores_codex":[0.9993269,0.00001545606,0.0001553501,0.0002449266,0.00006807718,0.0001892209],"domain_scores_gemma":[0.999414,0.00006023113,0.00008835712,0.0002491225,0.0001401285,0.00004813154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006759414,0.00003447851,0.001107147,0.00005534972,0.0000930607,5.376965e-7,0.000008546685,0.000003549652,0.984958,0.006442305,0.002855339,0.004374121],"study_design_scores_gemma":[0.0005674429,0.0001884672,0.0008686043,0.00004026539,0.00001319607,5.521566e-8,0.000003342997,0.000001286499,0.5953408,0.0000811225,0.4027966,0.00009880284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4444535,0.006280515,0.1974999,0.006383002,0.001381001,0.3419205,0.001176065,0.0002443801,0.0006610203],"genre_scores_gemma":[0.7754245,0.0002390389,0.005441174,0.0002906729,0.0008395081,0.2168785,0.000003500152,0.00005714125,0.0008259641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3999412,"threshold_uncertainty_score":0.3299906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03585890659757376,"score_gpt":0.343955756398991,"score_spread":0.3080968498014173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}