{"id":"W2283193718","doi":"10.1101/pdb.prot078329","title":"Tissue Dissociation for Metastasis Studies","year":2016,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Viability assay; Cell sorting; Dissociation (chemistry); Trypan blue; Metastasis; Cell; Chemistry; Suspension culture; Suspension (topology); Staining; Fluorescence; Biophysics; Cell biology; Pathology; Cell culture; Cancer research; Molecular biology; Biology; Medicine; Biochemistry; Cancer; Mathematics; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001673465,0.001877962,0.001233368,0.002356739,0.00160438,0.001179037,0.001731796,0.001588719,0.03516718],"category_scores_gemma":[0.001411003,0.0008124498,0.001361573,0.001567333,0.000752476,0.0009662851,0.001438454,0.00498243,0.02623675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006423009,"about_ca_system_score_gemma":0.001037092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001163082,"about_ca_topic_score_gemma":0.002367538,"domain_scores_codex":[0.9979593,0.0003151803,0.0001916589,0.0005131616,0.0007184976,0.0003021711],"domain_scores_gemma":[0.9988421,0.0002467477,0.0001101677,0.0003439052,0.0002857826,0.0001714343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003483477,0.0002895645,0.0005720352,0.0010402,0.0000747408,0.0007572513,0.0002194227,0.0003522839,0.9641936,0.003936724,0.008775851,0.01943996],"study_design_scores_gemma":[0.0001554121,0.001119009,0.004603341,0.0004660516,0.0001768855,0.005809066,0.0002098243,0.002318942,0.6716577,0.002784931,0.310607,0.00009185269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.0878767,0.04328191,0.7344548,0.002344324,0.005626388,0.01104735,0.02250321,0.006328866,0.08653651],"genre_scores_gemma":[0.206215,0.04616924,0.5764043,0.003759536,0.0007970745,0.0207545,0.05534453,0.003826476,0.08672933],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.03516718,"threshold_uncertainty_score":0.117646,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03585890659757376,"score_gpt":0.343955756398991,"score_spread":0.3080968498014173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}