{"id":"W2283321373","doi":"10.1242/jcs.170589","title":"Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent MRTF-A nuclear accumulation","year":2016,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Canada Foundation for Innovation","keywords":"Biology; Myofibroblast; Cell biology; Internal medicine; Fibrosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001047848,0.0002478732,0.0001546853,0.0001993083,0.0001866606,0.0003234559,0.0002226634,0.0002848974,0.001264175],"category_scores_gemma":[0.0001072715,0.0001474976,0.0001553663,0.0001008749,0.0002097051,0.0001591465,0.0002372855,0.0003397017,0.0005927865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004097588,"about_ca_system_score_gemma":0.0002023537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001137824,"about_ca_topic_score_gemma":0.001508525,"domain_scores_codex":[0.9998897,0.00001804632,0.00001077998,0.00002534838,0.00002697101,0.00002920553],"domain_scores_gemma":[0.9998695,0.0000162461,0.00004569774,0.00001570969,0.00001358424,0.00003936845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002867741,0.000007130431,0.0001210591,0.0000147904,0.000001623261,0.00003546869,0.00000358093,0.00002051829,0.9993844,0.00007802519,0.00001374617,0.0002908747],"study_design_scores_gemma":[0.000006570905,0.00007022715,0.01099139,0.000006452514,0.000009021357,0.0001580649,0.0000263446,0.0008649703,0.9855124,0.00003651038,0.002314384,0.000003630851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901555,0.002436145,0.004563319,0.00009496909,0.00002680998,0.00001974337,0.0004396254,0.0001292076,0.002134725],"genre_scores_gemma":[0.9944277,0.0003803997,0.001590483,0.00006043806,0.000005395737,0.00001813783,0.000897157,0.00002157733,0.002598567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001264175,"threshold_uncertainty_score":0.004229128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01628313282996232,"score_gpt":0.2723360386656506,"score_spread":0.2560529058356883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}