{"id":"W2283520088","doi":"10.1042/bss0670015","title":"Alzheimer's disease: inside, outside, upside down","year":2001,"lang":"en","type":"review","venue":"Biochemical Society Symposia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"","keywords":"Endoplasmic reticulum; Intracellular; Rage (emotion); Cell biology; Amyloid beta; Calcium in biology; Glycation; BETA (programming language); Receptor; Senile plaques; Cell; Neurotoxicity; Chemistry; Disease; Biology; Biochemistry; Alzheimer's disease; Peptide; Neuroscience; Medicine; Internal medicine; Toxicity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002300209,0.0007231268,0.0007590287,0.000929912,0.0003237829,0.000853183,0.0003887068,0.0007352876,0.005224434],"category_scores_gemma":[0.0003292723,0.0001525859,0.0001715238,0.001382867,0.0004291481,0.001430251,0.0004347426,0.0007410266,0.004210433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004047097,"about_ca_system_score_gemma":0.0006435605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006636961,"about_ca_topic_score_gemma":0.001348868,"domain_scores_codex":[0.9999003,0.00002069263,0.000009987331,0.00001571539,0.00004190072,0.00001124247],"domain_scores_gemma":[0.9999243,0.00001907249,0.000009046515,0.000004104915,0.00002659367,0.00001682877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007694201,0.00004286007,0.0001849464,0.006050441,0.00003080577,0.0002620564,0.0001450709,0.0001417082,0.003916895,0.00522338,0.06779347,0.9161314],"study_design_scores_gemma":[0.000006449191,0.00003097154,0.0004834376,0.0008366507,0.00001745608,0.0006275891,0.00008060064,0.00001641598,0.0002348223,0.001547158,0.9961152,0.000003241154],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002419712,0.9924337,0.0001456181,0.0005420787,0.0009623293,0.000004541349,0.000009581379,0.00001263356,0.005647588],"genre_scores_gemma":[0.001782495,0.9903965,0.0002819241,0.000507428,0.0007001502,0.000006150381,0.00001582959,0.000002531273,0.006307048],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005224434,"threshold_uncertainty_score":0.01747745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05623265758280861,"score_gpt":0.3626165406060399,"score_spread":0.3063838830232313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}