{"id":"W2283520088","doi":"10.1042/bss0670015","title":"Alzheimer's disease: inside, outside, upside down","year":2001,"lang":"en","type":"review","venue":"Biochemical Society Symposia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"","keywords":"Endoplasmic reticulum; Intracellular; Rage (emotion); Cell biology; Amyloid beta; Calcium in biology; Glycation; BETA (programming language); Receptor; Senile plaques; Cell; Neurotoxicity; Chemistry; Disease; Biology; Biochemistry; Alzheimer's disease; Peptide; Neuroscience; Medicine; Internal medicine; Toxicity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001867255,0.001198268,0.002662496,0.0001069009,0.0002315283,0.0001094429,0.0004858042,0.0009737145,0.0005410108],"category_scores_gemma":[0.00009436253,0.000907656,0.004253066,0.0008892504,0.000458568,0.000112858,0.0003992532,0.001059491,0.001286509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005730764,"about_ca_system_score_gemma":0.001897134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004344745,"about_ca_topic_score_gemma":3.817342e-7,"domain_scores_codex":[0.9948668,0.0001382455,0.001004006,0.001428612,0.001260274,0.001302099],"domain_scores_gemma":[0.9951586,0.0002300332,0.0003346806,0.001378195,0.0002045254,0.002693983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003159567,0.003327871,0.0008452525,0.02145638,0.1089346,0.002145717,0.00006232,1.184832e-7,0.00001739446,0.000277026,0.3278781,0.5347393],"study_design_scores_gemma":[0.001217458,0.0001167628,0.0001098593,0.00883105,0.02531813,0.0001697073,0.00001333184,0.000007232684,0.0000352469,0.00006037968,0.9632868,0.000834079],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003395964,0.9937966,0.000004927226,0.0003755882,0.0001534352,0.002422198,0.0004416106,0.0003202143,0.002451414],"genre_scores_gemma":[0.0003010766,0.9926482,0.0004903512,0.0004465403,0.001036005,0.0006234556,0.003913015,0.0002293296,0.0003119727],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6354086,"threshold_uncertainty_score":0.9994911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05623265758280861,"score_gpt":0.3626165406060399,"score_spread":0.3063838830232313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}