{"id":"W2283762496","doi":"10.1021/jacs.5b10939","title":"Aptamer and Antisense-Mediated Two-Dimensional Isolation of Specific Cancer Cell Subpopulations","year":2016,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Aptamer; Cell sorting; Cancer cell; Chemistry; Phenotype; Cell; Cancer; DNA; Computational biology; Molecular biology; Circulating tumor cell; Cancer research; Biology; Gene; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002151703,0.0002534558,0.0002104195,0.0002402964,0.0001565195,0.0003600646,0.0002212556,0.0002581831,0.0005267373],"category_scores_gemma":[0.0001911318,0.0001600656,0.00018442,0.0001498998,0.0002306802,0.0002441527,0.0002700434,0.0005600615,0.0002212971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002271469,"about_ca_system_score_gemma":0.0002741072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004626212,"about_ca_topic_score_gemma":0.001505409,"domain_scores_codex":[0.9998354,0.00002448688,0.00001620402,0.00004272359,0.00005740618,0.00002367705],"domain_scores_gemma":[0.9998856,0.00003050182,0.000027205,0.00001866969,0.00001833747,0.00001975696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002119931,0.00001127879,0.00007699442,0.000009982085,0.000001914083,0.000007938052,0.00001606338,0.00006346994,0.9979627,0.0002524596,0.00004022961,0.00153581],"study_design_scores_gemma":[0.00001522803,0.00008895229,0.001006689,0.000001818941,0.00000564041,0.00009361649,0.00001116917,0.0024635,0.9936387,0.0001324996,0.00253574,0.000006322286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8488134,0.001414217,0.1450452,0.0003980906,0.0001529133,0.0002713134,0.0005726414,0.0003913824,0.002940909],"genre_scores_gemma":[0.8876717,0.00116697,0.1016231,0.0003620872,0.00004574814,0.0004641238,0.001050832,0.000116982,0.007498542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005267373,"threshold_uncertainty_score":0.001762092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01599946088543307,"score_gpt":0.2768507132337987,"score_spread":0.2608512523483656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}