{"id":"W2284175677","doi":"10.1152/ajpgi.2001.280.3.g315","title":"IV. Modulation of intestinal inflammation by stress: basic mechanisms and clinical relevance","year":2001,"lang":"en","type":"review","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":223,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"","keywords":"Inflammation; Proinflammatory cytokine; Stimulus (psychology); Irritable bowel syndrome; Inflammatory bowel disease; Medicine; Vasopressin; Immune system; Intestinal permeability; Inflammatory response; Neuropeptide; Immunology; Internal medicine; Neuroscience; Endocrinology; Disease; Biology; Psychology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001771529,0.0005146468,0.002374439,0.0002468231,0.0001008142,0.00001871491,0.0004347978,0.0001240876,0.00003863777],"category_scores_gemma":[0.001326403,0.0003915918,0.0004214679,0.0003736956,0.001719349,0.0001909011,0.0002297679,0.0009262679,0.000004749873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003952359,"about_ca_system_score_gemma":0.0001746132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004533321,"about_ca_topic_score_gemma":0.000002228404,"domain_scores_codex":[0.9956059,0.001429387,0.001625887,0.0006832898,0.0002392781,0.0004162647],"domain_scores_gemma":[0.9924263,0.002903787,0.003959047,0.0002846718,0.0002132654,0.0002129132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.0005692294,0.0001468032,0.00006104803,0.0008240129,0.00005823132,0.0000330974,0.00002299106,0.00001682146,0.1536473,0.0003572919,0.0000510046,0.8442122],"study_design_scores_gemma":[0.01464992,0.2308281,0.1883878,0.1519267,0.01126803,0.1205265,0.002742379,0.0153406,0.01015577,0.03814147,0.2056957,0.01033704],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.4568128,0.5395052,0.002236578,0.00007897656,0.0004143936,0.0006730459,0.000188905,0.00004718131,0.00004296407],"genre_scores_gemma":[0.07032401,0.9270241,0.002169922,0.00005825958,0.0003371995,0.000009907663,0.00001780988,0.0000341473,0.00002469387],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8338752,"threshold_uncertainty_score":0.9998536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03316245037004011,"score_gpt":0.3131978659937782,"score_spread":0.2800354156237381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}