{"id":"W2284532483","doi":"10.1161/hyp.60.suppl_1.a510","title":"Abstract 510: Altered c-Src Activity by Aldosterone in Vascular Smooth Muscle Cells From SHR Involves PDGFR, C-terminal Src Kinase (Csk) and Csk-binding Protein (CBP).","year":2012,"lang":"en","type":"article","venue":"Hypertension","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Proto-oncogene tyrosine-protein kinase Src; Phosphorylation; Kinase; Cell biology; Aldosterone; Tyrosine-protein kinase CSK; Vascular smooth muscle; Signal transduction; Activator (genetics); Chemistry; Src family kinase; Biology; SH3 domain; Biochemistry; Endocrinology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009900335,0.000316407,0.0003275147,0.0001758073,0.000215561,0.0002133433,0.0001279628,0.000231787,0.002970397],"category_scores_gemma":[0.00008531892,0.0001425786,0.0002729193,0.0001201737,0.000247765,0.0002003811,0.0001998337,0.0007106074,0.0006051366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001952671,"about_ca_system_score_gemma":0.0001218298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001174219,"about_ca_topic_score_gemma":0.001174587,"domain_scores_codex":[0.9998046,0.00002076458,0.00001908313,0.00004226935,0.00006768919,0.0000456753],"domain_scores_gemma":[0.9999081,0.000009384522,0.00002196225,0.00001164666,0.00001365343,0.00003524759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007544507,0.00001380545,0.0003607717,0.00002381765,0.000004304169,0.00007001579,0.00001023923,0.000004922898,0.998942,0.00002163097,0.00003799971,0.0004350586],"study_design_scores_gemma":[0.00003046297,0.0005636606,0.1098053,0.00001117303,0.00004120326,0.001226487,0.00009020087,0.0005924026,0.8852326,0.00008883928,0.002306653,0.00001103918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964302,0.000874167,0.000822254,0.0001421168,0.00005400803,0.00001259218,0.0006085292,0.00004192877,0.001014203],"genre_scores_gemma":[0.9935856,0.0006476415,0.0008340145,0.0001330482,0.00003957011,0.00003198662,0.001082972,0.00001972139,0.003625375],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002970397,"threshold_uncertainty_score":0.009936988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03438654050652172,"score_gpt":0.2470691808490191,"score_spread":0.2126826403424974,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}