{"id":"W2285179530","doi":"10.3747/co.23.2836","title":"Cancer Evolution–Development: Experience of Hepatitis B Virus–Induced Hepatocarcinogenesis","year":2016,"lang":"en","type":"review","venue":"Current Oncology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Transactivation; Cancer; Biology; Inflammation; Tumor microenvironment; Carcinogenesis; Immune system; Proinflammatory cytokine; Cancer stem cell; Cancer research; Immunology; Genetics; Gene; Transcription factor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002595795,0.0006363028,0.003657385,0.0004540573,0.0001478209,0.000006062532,0.0003853326,0.000508664,0.0007857674],"category_scores_gemma":[0.0003498002,0.0004614371,0.0005282598,0.0004932382,0.0003298299,0.0000712544,0.0003628744,0.0004065549,0.0003632209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002720636,"about_ca_system_score_gemma":0.004084162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001608325,"about_ca_topic_score_gemma":0.00303907,"domain_scores_codex":[0.9962605,0.0002990639,0.001504862,0.0007684057,0.0005294808,0.000637709],"domain_scores_gemma":[0.9974973,0.000293526,0.0009242197,0.0005974136,0.0004350722,0.0002525002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001641942,0.0002833343,0.03836188,0.01070673,0.0003701613,0.00002764253,0.0006261637,5.29341e-9,0.00002044163,0.00007239935,0.001542157,0.9479727],"study_design_scores_gemma":[0.0004743099,0.0002144704,0.004855832,0.02581748,0.000772127,0.00004251991,0.000009025867,8.999097e-7,0.00008485156,0.000007437974,0.9673006,0.0004204613],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003391957,0.9910877,0.00008796279,0.00004352221,0.00303392,0.001454068,0.0002186036,0.00007729628,0.0006049927],"genre_scores_gemma":[0.001375015,0.9949547,0.0001771154,0.00002836239,0.0005756238,0.002483168,0.00005905152,0.0000814727,0.0002655002],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9657584,"threshold_uncertainty_score":0.9997838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2506102847116137,"score_gpt":0.4726326812562246,"score_spread":0.2220223965446109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}