{"id":"W2285359655","doi":"10.1038/gt.2015.95","title":"Lymphopoiesis in transgenic mice over-expressing Artemis","year":2015,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institut National Du Cancer; Ligue Contre le Cancer; Institute of Cancer Research; Institut National de la Santé et de la Recherche Médicale","keywords":"Transgene; Biology; Genetic enhancement; Lymphopoiesis; Genetically modified mouse; Enhancer; Severe combined immunodeficiency; Haematopoiesis; Homologous recombination; Transplantation; Gene; Stem cell; Cancer research; Humanized mouse; Gene targeting; Immunology; Genetics; Gene expression; Medicine; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000347098,0.0007070916,0.0004836006,0.001600546,0.0004242761,0.000678744,0.000443172,0.0009680105,0.004913701],"category_scores_gemma":[0.0002539166,0.0004070897,0.0004882311,0.0003921885,0.0009363172,0.0006992516,0.0003254693,0.002146428,0.001056179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004854126,"about_ca_system_score_gemma":0.0003640717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005991402,"about_ca_topic_score_gemma":0.0005949031,"domain_scores_codex":[0.999624,0.00005503599,0.00003843022,0.0001053625,0.00008814467,0.00008903744],"domain_scores_gemma":[0.9994261,0.0001330058,0.0001751035,0.00005661542,0.00003935877,0.0001698191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005041284,0.00006744236,0.0001384539,0.00002911774,0.000006985259,0.0001211756,0.00004546299,0.00006051655,0.9974536,0.0005101505,0.00006007534,0.001002808],"study_design_scores_gemma":[0.0001542022,0.0004956672,0.001029821,0.00001381019,0.00006491596,0.0003986164,0.0000621574,0.0008044313,0.9932546,0.0002997984,0.003410422,0.00001172553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816002,0.001552505,0.006910454,0.0004863762,0.0002585059,0.0001387336,0.001935832,0.0008285809,0.006288927],"genre_scores_gemma":[0.9729866,0.0009896249,0.004212711,0.000255004,0.00008767845,0.0001887925,0.00125545,0.0003168109,0.01970728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004913701,"threshold_uncertainty_score":0.01643795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08276522852367603,"score_gpt":0.3484479986844704,"score_spread":0.2656827701607944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}