{"id":"W2285359655","doi":"10.1038/gt.2015.95","title":"Lymphopoiesis in transgenic mice over-expressing Artemis","year":2015,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institut National Du Cancer; Ligue Contre le Cancer; Institute of Cancer Research; Institut National de la Santé et de la Recherche Médicale","keywords":"Transgene; Biology; Genetic enhancement; Lymphopoiesis; Genetically modified mouse; Enhancer; Severe combined immunodeficiency; Haematopoiesis; Homologous recombination; Transplantation; Gene; Stem cell; Cancer research; Humanized mouse; Gene targeting; Immunology; Genetics; Gene expression; Medicine; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000414764,0.0001368429,0.000276022,0.0001735472,0.00004040462,0.00003042986,0.000118282,0.00009790116,0.0004269739],"category_scores_gemma":[0.00001866261,0.0001159788,0.00009111252,0.0003173416,0.00005144415,0.00007723855,0.00001642029,0.0001532814,0.0001107516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001891701,"about_ca_system_score_gemma":0.0003080939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006143709,"about_ca_topic_score_gemma":0.00009366536,"domain_scores_codex":[0.9987251,0.00006381545,0.0002199139,0.0002469998,0.0003824528,0.0003617014],"domain_scores_gemma":[0.9993396,0.00003560324,0.00002885376,0.0003005898,0.00006167316,0.0002336261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002230208,0.0003336429,0.01507383,0.0000259518,0.00008441348,0.00005537973,0.003370262,0.00002280246,0.859855,0.00001733384,0.004768724,0.1141625],"study_design_scores_gemma":[0.02185852,0.0007347148,0.04735028,0.0001332295,0.00002748798,0.00008669583,0.0005663373,0.0007150499,0.6145148,0.0006342895,0.3128793,0.0004993241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887524,0.005434013,0.0000682175,0.0007697367,0.00009487026,0.000271442,0.000006760839,0.00004599839,0.004556554],"genre_scores_gemma":[0.9952562,0.00177773,0.0005109925,0.0008818992,0.0003100153,0.00002791979,0.00001001394,0.00003598354,0.001189206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3081105,"threshold_uncertainty_score":0.472948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08276522852367603,"score_gpt":0.3484479986844704,"score_spread":0.2656827701607944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}