{"id":"W2285724633","doi":"10.5772/62337","title":"Gold Nanoparticles Impinge on Nucleoli and the Stress Response in MCF7 Breast Cancer Cells","year":2016,"lang":"en","type":"review","venue":"Nanobiomedicine","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nucleolus; Colloidal gold; Cell biology; Ribosome; Cancer cell; Ribosome biogenesis; Organelle; Chemistry; Nucleus; Ribosomal protein; Biology; Biophysics; RNA; Nanoparticle; Cancer; Nanotechnology; Materials science; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004903683,0.0002642428,0.0005730847,0.000110041,0.00004931041,0.00001727869,0.0002513071,0.0002258913,0.00004528119],"category_scores_gemma":[0.00003102217,0.0001309596,0.0001099558,0.0001896337,0.0003946537,0.000002320992,0.00008365422,0.000129488,0.0000164272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005860174,"about_ca_system_score_gemma":0.000181341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005106985,"about_ca_topic_score_gemma":0.00002288941,"domain_scores_codex":[0.9985754,0.000256355,0.0003607561,0.0004206892,0.0001340273,0.0002527691],"domain_scores_gemma":[0.9990914,0.000091308,0.0001834875,0.0005164579,0.00004049052,0.00007684969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001111803,0.00006886759,0.00001191237,0.0009187916,0.0001023456,0.00000731023,0.00004831652,4.310932e-7,0.03641795,0.00007083928,0.004701165,0.9565403],"study_design_scores_gemma":[0.001565061,0.0001332193,0.0001516343,0.005645094,0.0001068428,0.00002268179,0.00001888377,0.000001101531,0.001442397,0.000005735389,0.9907088,0.0001985896],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009752244,0.9877779,0.00000238448,0.001135282,0.0002367219,0.0004981764,0.000490923,0.000006496966,0.00009990411],"genre_scores_gemma":[0.01073754,0.9870387,0.000004148334,0.0002460694,0.000408569,0.0002438209,0.0000354531,0.00003626,0.001249386],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9860076,"threshold_uncertainty_score":0.5340378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01553795452628834,"score_gpt":0.3129675756355161,"score_spread":0.2974296211092278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}