{"id":"W2285996315","doi":"10.1242/dev.133165","title":"Drosophila astrocytes cover specific territories of CNS neuropil and are instructed to differentiate by Prospero, a key effector of Notch","year":2016,"lang":"en","type":"article","venue":"Development","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Biotechnology and Biological Sciences Research Council; Canada Foundation for Innovation; McGill University","keywords":"Biology; Neuropil; Astrocyte; Effector; Notch signaling pathway; Neuroscience; Cell fate determination; Cell biology; Central nervous system; Signal transduction; Genetics; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005406415,0.0001727213,0.000229808,0.0001043442,0.00007892466,0.00003261584,0.0001538917,0.000033872,0.0000745709],"category_scores_gemma":[0.0001504949,0.0001258813,0.00002652598,0.0001686859,0.00006840829,0.0001159191,0.0001125297,0.00004872381,0.00003166652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002425892,"about_ca_system_score_gemma":0.00003325199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001049801,"about_ca_topic_score_gemma":0.000003362604,"domain_scores_codex":[0.9986013,0.00008469716,0.0003952069,0.0003824462,0.0003580493,0.0001783171],"domain_scores_gemma":[0.9993424,0.00009864195,0.0001979163,0.0001891104,0.00006565751,0.0001062709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006332404,0.0000431934,0.00254714,0.00003363624,0.00000264656,0.00000308491,0.000240761,0.000001205328,0.9948543,0.0005440774,0.0003810718,0.001285588],"study_design_scores_gemma":[0.0006063965,0.0001052256,0.05291937,0.00005916809,0.000002309828,0.000004773132,0.000004121632,0.000006343437,0.9386257,0.00001452946,0.007525312,0.0001267712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976959,0.000006442647,0.001102007,0.0002943767,0.00037927,0.0003518427,0.00008825237,0.00004477568,0.00003719869],"genre_scores_gemma":[0.9983376,0.00003292256,0.0009683996,0.0001587483,0.00003094336,0.00002804543,0.000004144418,0.00002050527,0.0004186392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05622859,"threshold_uncertainty_score":0.513329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01702556179175651,"score_gpt":0.2118219441068634,"score_spread":0.1947963823151069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}