{"id":"W2285996315","doi":"10.1242/dev.133165","title":"Drosophila astrocytes cover specific territories of CNS neuropil and are instructed to differentiate by Prospero, a key effector of Notch","year":2016,"lang":"en","type":"article","venue":"Development","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Biotechnology and Biological Sciences Research Council; Canada Foundation for Innovation; McGill University","keywords":"Biology; Neuropil; Astrocyte; Effector; Notch signaling pathway; Neuroscience; Cell fate determination; Cell biology; Central nervous system; Signal transduction; Genetics; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003928608,0.0002575962,0.0001266748,0.0001778881,0.0002376283,0.0002000331,0.0001128354,0.0001304243,0.0008084552],"category_scores_gemma":[0.00004402053,0.0001639217,0.0001390627,0.00005654321,0.0001620515,0.0001357678,0.0002636942,0.0003130513,0.0003081858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001796439,"about_ca_system_score_gemma":0.0001189648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006578549,"about_ca_topic_score_gemma":0.002789535,"domain_scores_codex":[0.9999512,0.000004144081,0.000004132983,0.00001424655,0.00001653773,0.00000960414],"domain_scores_gemma":[0.9999509,0.000005931575,0.00001790974,0.000004982147,0.000006319744,0.00001400467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002537586,0.000002500901,0.0004712789,0.00001429752,0.000001485623,0.00004603892,0.00001494765,0.00003384621,0.998311,0.0001412272,0.00001911437,0.0009189318],"study_design_scores_gemma":[0.00000894439,0.00006897318,0.01718821,0.000009000565,0.00001250108,0.0004364301,0.00005611208,0.001009805,0.9768779,0.0001277594,0.004199294,0.000005043922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914482,0.0008071288,0.004064291,0.00003496925,0.00001260561,0.0000137359,0.000338174,0.00004405641,0.003236854],"genre_scores_gemma":[0.9849067,0.0008081546,0.006794598,0.00004651761,0.000005595793,0.00001791176,0.0005310024,0.0000271168,0.006862399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008084552,"threshold_uncertainty_score":0.002704501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01702556179175651,"score_gpt":0.2118219441068634,"score_spread":0.1947963823151069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}