{"id":"W2286216520","doi":"10.1371/journal.pone.0144810","title":"MicroRNA Expression Is Altered in an Ovalbumin-Induced Asthma Model and Targeting miR-155 with Antagomirs Reveals Cellular Specificity","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Health and Medical Research Council; Medical Research Council; Canadian Institutes of Health Research","keywords":"Antagomir; microRNA; Ovalbumin; miR-155; Immune system; Inflammation; Immunology; Cancer research; Medicine; Biology; Phenotype; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002229467,0.0001846775,0.0002111483,0.00005650997,0.00004626361,0.00003296165,0.0001288396,0.0001504428,0.000007994616],"category_scores_gemma":[0.00003890578,0.0001752627,0.00002582038,0.00007307255,0.0000431527,0.00001738332,0.00009554205,0.00009687586,0.000003757569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003387957,"about_ca_system_score_gemma":0.00006198788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001071671,"about_ca_topic_score_gemma":0.00001293224,"domain_scores_codex":[0.9987207,0.0000890177,0.0002416663,0.0004909382,0.0002112273,0.0002464638],"domain_scores_gemma":[0.999177,0.000004755866,0.0001231262,0.0003666723,0.0001282332,0.0002001526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003235842,0.0004301393,0.006092228,0.0000515246,0.00002602002,0.000006140052,0.0002614878,0.00008701051,0.9923808,0.00000178811,0.0002985714,0.00004068098],"study_design_scores_gemma":[0.0009859775,0.000199033,0.002149248,0.0001239593,0.00002096679,0.000002637836,0.00009888874,0.004106158,0.9919689,0.00006676749,0.00003536552,0.0002420432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986197,0.0005210187,0.0003093247,0.00008436436,0.00001424446,0.000334925,0.00002886029,0.0000146357,0.00007291654],"genre_scores_gemma":[0.9880453,0.00002533138,0.01136548,0.00007954663,0.0001546797,0.00001688207,0.0001902063,0.00003693523,0.00008565772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01105616,"threshold_uncertainty_score":0.7147005,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04929124120444181,"score_gpt":0.2465410170686989,"score_spread":0.197249775864257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}