{"id":"W2287650212","doi":"10.1021/acsnano.5b07102","title":"Enzyme-Powered Three-Dimensional DNA Nanomachine for DNA Walking, Payload Release, and Biosensing","year":2016,"lang":"en","type":"article","venue":"ACS Nano","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":365,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Brock University; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Payload (computing); Biosensor; Nanotechnology; DNA; Enzyme; Biophysics; Materials science; Chemistry; Computer science; Biology; Biochemistry; Computer network","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000211514,0.000237185,0.0002274264,0.00006878685,0.0001703504,0.00002310429,0.0001120893,0.0002283559,0.000002293422],"category_scores_gemma":[0.0002197344,0.0001563567,0.0001228112,0.00008974995,0.0001643749,0.000008036974,0.0001282208,0.00004929668,0.000002943755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001563139,"about_ca_system_score_gemma":0.00003657047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001025894,"about_ca_topic_score_gemma":0.00007066008,"domain_scores_codex":[0.9987158,0.00003895427,0.0002509456,0.0005407314,0.0001283173,0.0003252695],"domain_scores_gemma":[0.9991803,0.00005719161,0.0001334099,0.0003935283,0.0001404006,0.00009519286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001255794,0.00003324435,0.0003970015,0.000007426107,0.0000609663,0.000003349309,0.000003425602,1.599508e-7,0.9577758,0.00006653539,0.001839671,0.03968687],"study_design_scores_gemma":[0.0006956303,0.0002832594,0.0004725872,0.00005675854,0.00004626797,0.00004001622,0.000004134832,0.0000281091,0.9708285,0.0005451918,0.02671026,0.0002892478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994762,0.0009177038,0.002937157,0.0008362811,0.00009752149,0.0002173188,0.00007367964,0.0000699873,0.00008835704],"genre_scores_gemma":[0.9903547,0.0001754335,0.007825739,0.0004287604,0.0002073247,0.000008018801,0.00008470169,0.00003395438,0.0008813809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03939762,"threshold_uncertainty_score":0.6376041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008208282233540443,"score_gpt":0.2492647344532266,"score_spread":0.2410564522196862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}