{"id":"W2288156681","doi":"10.1093/neuonc/nox025","title":"Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG","year":2017,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"EMD Serono; National Cancer Institute; NRG Oncology; Merck KGaA","keywords":"Temozolomide; Glioblastoma; Oncology; Internal medicine; Medicine; Adjuvant; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003779578,0.0003006487,0.001633437,0.0005858233,0.0001295635,0.00001667502,0.0003071255,0.0002871005,0.0002424613],"category_scores_gemma":[0.0005046895,0.0001922071,0.0005095223,0.0004065551,0.0006581647,0.00009584725,0.000227166,0.0004022903,0.000004873081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002919081,"about_ca_system_score_gemma":0.0005186101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001703809,"about_ca_topic_score_gemma":0.002063376,"domain_scores_codex":[0.9978776,0.0002555664,0.0007198605,0.0005114845,0.0002289429,0.0004065528],"domain_scores_gemma":[0.9965913,0.001233163,0.0008026429,0.001043854,0.0001367273,0.0001922789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001398258,0.002323158,0.7717508,0.00004389919,0.00235083,0.002686627,0.002313375,0.00004881691,0.09994697,0.00002128301,0.003350991,0.113765],"study_design_scores_gemma":[0.009440542,0.005688798,0.9653162,0.00003857462,0.002228579,0.0001430917,0.000346199,0.0008611975,0.0144117,0.000078344,0.001318053,0.0001287254],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892336,0.0005890916,0.000001676161,0.008043949,0.0001260816,0.0006800775,0.0001302997,0.00001576937,0.001179456],"genre_scores_gemma":[0.9980107,0.0003862377,0.0001052917,0.001278089,0.00006006999,0.0001091734,0.00001798658,0.00002576483,0.000006674436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1935654,"threshold_uncertainty_score":0.7837976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02028367957213684,"score_gpt":0.3466698246597023,"score_spread":0.3263861450875654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}